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ChEMBL ligand: CHEMBL428593 (1-mono(cis-9-octacenoyl)glycerol, 1-monoolein, 1-monooleoyl-rac-glycerol, .alpha.-monoolein, FEMA NO. 2526, Glycerol 1-monooleate, Glycerol monooleate, Glyceryl 1-oleate, Glyceryl mono-oleate, Glyceryl monooleate, Glyceryl monooleate 40, Glyceryl monooleate 40%, Glyceryl monooleate 60, Glyceryl monooleate 90, Glyceryl monooleate 90%, Glyceryl oleate, Monolein, Mono-olein, Monoolein, NSC-406285, Olein, Rac-1-monooleoylglycerol) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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diacylglycerol kinase alpha/Diacylglycerol kinase alpha in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4105787] [GtoPdb: 3256] [UniProtKB: P23743] | ||||||||
ChEMBL | Inhibition of DGKalpha in human erythrocytes using OAG as substrate preincubated for 1 min followed by OAG addition and measured after 8 mins in presence of [gamma-32P]ATP | B | 4.04 | pKi | 91000 | nM | Ki | Eur J Med Chem (2019) 164: 378-390 [PMID:30611057] |
GPR119 in Human [GtoPdb: 126] [UniProtKB: Q8TDV5] | ||||||||
GtoPdb | - | - | 5.6 | pEC50 | - | - | - | J Clin Endocrinol Metab (2011) 96: E1409-17 [PMID:21778222] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]