Synonyms: 18F-flutemetamol | [18F]flutemetamol | flutemetamol F18
flutemetamol is an approved drug (FDA (2013), EMA (2014))
Compound class:
Synthetic organic
Comment: Flutemetamol F-18 (Vizamyl GE Healthcare) is a positron emission tomography (PET) radiotracer approved in 2013 that binds to amyloid plaques in Alzheimer's disease neurodegeneration. However imaging agents have been granted only narrow approval since they can not be used to definitively diagnose Alzheimer's disease or to gauge treatment effectiveness, only to support other diagnostic criteria [2].
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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Classification | |
Compound class | Synthetic organic |
Approved drug? | Yes (FDA (2013), EMA (2014)) |
IUPAC Name |
2-[3-(18F)fluoro-4-(methylamino)phenyl]-1,3-benzothiazol-6-ol |
International Nonproprietary Names | |
INN number | INN |
9169 | flutemetamol (18F) |
Synonyms |
18F-flutemetamol | [18F]flutemetamol | flutemetamol F18 |
Database Links | |
CAS Registry No. | 765922-62-1 (source: SciFinder) |
ChEMBL Ligand | CHEMBL2042122 |
DrugCentral Ligand | 4301 |
GtoPdb PubChem SID | 178103914 |
PubChem CID | 15950376 |
Search Google for chemical match using the InChIKey | VVECGOCJFKTUAX-HUYCHCPVSA-N |
Search Google for chemicals with the same backbone | VVECGOCJFKTUAX |
Search PubMed clinical trials | flutemetamol |
Search PubMed titles | flutemetamol |
Search PubMed titles/abstracts | flutemetamol |
UniChem Compound Search for chemical match using the InChIKey | VVECGOCJFKTUAX-HUYCHCPVSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | VVECGOCJFKTUAX-HUYCHCPVSA-N |
Wikipedia | Flutemetamol (18F) |