1. Al-Obeidi F, Hruby VJ, Castrucci AM, Hadley ME. (1989) Design of potent linear α-melanotropin 4-10 analogues modified in positions 5 and 10.
J Med Chem, 32: 174-179.
[PMID:2535874]
2. Benoit SC, Schwartz MW, Lachey JL, Hagan MM, Rushing PA, Blake KA, Yagaloff KA, Kurylko G, Franco L, Danhoo W et al.. (2000) A novel selective melanocortin-4 receptor agonist reduces food intake in rats and mice without producing aversive consequences.
J Neurosci, 20 (9): 3442-8.
[PMID:10777807]
3. Boston BA, Cone RD. (1996) Characterization of melanocortin receptor subtype expression in murine adipose tissues and in the 3T3-L1 cell line.
Endocrinology, 137 (5): 2043-50.
[PMID:8612546]
4. Böhm M, Eickelmann M, Li Z, Schneider SW, Oji V, Diederichs S, Barsh GS, Vogt A, Stieler K, Blume-Peytavi U et al.. (2005) Detection of functionally active melanocortin receptors and evidence for an immunoregulatory activity of alpha-melanocyte-stimulating hormone in human dermal papilla cells.
Endocrinology, 146 (11): 4635-46.
[PMID:16081629]
5. Castejón-Griñán M, Herraiz C, Olivares C, Jiménez-Cervantes C, García-Borrón JC. (2018) cAMP-independent non-pigmentary actions of variant melanocortin 1 receptor: AKT-mediated activation of protective responses to oxidative DNA damage.
Oncogene, 37 (27): 3631-3646.
[PMID:29622793]
6. Castrucci AM, Hadley ME, Hruby VJ. (1984) Melanotropin bioassays: in vitro and in vivo comparisons.
Gen Comp Endocrinol, 55 (1): 104-11.
[PMID:6611282]
7. Catania A, Rajora N, Capsoni F, Minonzio F, Star RA, Lipton JM. (1996) The neuropeptide alpha-MSH has specific receptors on neutrophils and reduces chemotaxis in vitro.
Peptides, 17 (4): 675-9.
[PMID:8804079]
8. Chhajlani V. (1996) Distribution of cDNA for melanocortin receptor subtypes in human tissues.
Biochem Mol Biol Int, 38 (1): 73-80.
[PMID:8932521]
9. Chhajlani V, Wikberg JE. (1996) Molecular cloning and expression of the human melanocyte stimulating hormone receptor cDNA (FEBS 11553).
FEBS Lett, 390 (2): 238.
[PMID:8706868]
10. Conde-Frieboes K, Thøgersen H, Lau JF, Sensfuss U, Hansen TK, Christensen L, Spetzler J, Olsen HB, Nilsson C, Raun K et al.. (2012) Identification and in vivo and in vitro characterization of long acting and melanocortin 4 receptor (MC4-R) selective α-melanocyte-stimulating hormone (α-MSH) analogues.
J Med Chem, 55 (5): 1969-77.
[PMID:22335602]
11. Dinulescu DM, Cone RD. (2000) Agouti and agouti-related protein: analogies and contrasts.
J Biol Chem, 275 (10): 6695-8.
[PMID:10702221]
12. Hartmeyer M, Scholzen T, Becher E, Bhardwaj RS, Schwarz T, Luger TA. (1997) Human dermal microvascular endothelial cells express the melanocortin receptor type 1 and produce increased levels of IL-8 upon stimulation with alpha-melanocyte-stimulating hormone.
J Immunol, 159 (4): 1930-7.
[PMID:9257858]
13. Herpin TF, Yu G, Carlson KE, Morton GC, Wu X, Kang L, Tuerdi H, Khanna A, Tokarski JS, Lawrence RM et al.. (2003) Discovery of tyrosine-based potent and selective melanocortin-1 receptor small-molecule agonists with anti-inflammatory properties.
J Med Chem, 46 (7): 1123-6.
[PMID:12646021]
14. Hruby VJ, Lu D, Sharma SD, Castrucci AL, Kesterson RA, al-Obeidi FA, Hadley ME, Cone RD. (1995) Cyclic lactam alpha-melanotropin analogues of Ac-Nle4-cyclo[Asp5, D-Phe7,Lys10] alpha-melanocyte-stimulating hormone-(4-10)-NH2 with bulky aromatic amino acids at position 7 show high antagonist potency and selectivity at specific melanocortin receptors.
J Med Chem, 38 (18): 3454-61.
[PMID:7658432]
15. Jayawickreme CK, Jayawickreme SP, Lerner MR. (1998) Generation of multiuse peptide libraries for functional screenings.
Methods Mol Biol, 87: 107-18.
[PMID:9523265]
16. Kadekaro AL, Kavanagh R, Kanto H, Terzieva S, Hauser J, Kobayashi N, Schwemberger S, Cornelius J, Babcock G, Shertzer HG et al.. (2005) alpha-Melanocortin and endothelin-1 activate antiapoptotic pathways and reduce DNA damage in human melanocytes.
Cancer Res, 65 (10): 4292-9.
[PMID:15899821]
17. Kadekaro AL, Leachman S, Kavanagh RJ, Swope V, Cassidy P, Supp D, Sartor M, Schwemberger S, Babcock G, Wakamatsu K et al.. (2010) Melanocortin 1 receptor genotype: an important determinant of the damage response of melanocytes to ultraviolet radiation.
FASEB J, 24 (10): 3850-60.
[PMID:20519635]
18. Kask A, Mutulis F, Muceniece R, Pähkla R, Mutule I, Wikberg JE, Rägo L, Schiöth HB. (1998) Discovery of a novel superpotent and selective melanocortin-4 receptor antagonist (HS024): evaluation in vitro and in vivo.
Endocrinology, 139 (12): 5006-14.
[PMID:9832440]
19. Kiefer LL, Veal JM, Mountjoy KG, Wilkison WO. (1998) Melanocortin receptor binding determinants in the agouti protein.
Biochemistry, 37 (4): 991-7.
[PMID:9454589]
20. Kopanchuk S, Veiksina S, Petrovska R, Mutule I, Szardenings M, Rinken A, Wikberg JE. (2005) Co-operative regulation of ligand binding to melanocortin receptor subtypes: evidence for interacting binding sites.
Eur J Pharmacol, 512 (2-3): 85-95.
[PMID:15840392]
21. Kumar KG, Sutton GM, Dong JZ, Roubert P, Plas P, Halem HA, Culler MD, Yang H, Dixit VD, Butler AA. (2009) Analysis of the therapeutic functions of novel melanocortin receptor agonists in MC3R- and MC4R-deficient C57BL/6J mice.
Peptides, 30 (10): 1892-900.
[PMID:19646498]
22. Lu D, Willard D, Patel IR, Kadwell S, Overton L, Kost T, Luther M, Chen W, Woychik RP, Wilkison WO et al.. (1994) Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor.
Nature, 371 (6500): 799-802.
[PMID:7935841]
23. MacNeil DJ, Howard AD, Guan X, Fong TM, Nargund RP, Bednarek MA, Goulet MT, Weinberg DH, Strack AM, Marsh DJ et al.. (2002) The role of melanocortins in body weight regulation: opportunities for the treatment of obesity.
Eur J Pharmacol, 440 (2-3): 141-57.
[PMID:12007532]
24. Mountjoy KG, Bird IM, Rainey WE, Cone RD. (1994) ACTH induces up-regulation of ACTH receptor mRNA in mouse and human adrenocortical cell lines.
Mol Cell Endocrinol, 99 (1): R17-20.
[PMID:8187950]
25. Mountjoy KG, Kong PL, Taylor JA, Willard DH, Wilkison WO. (2001) Melanocortin receptor-mediated mobilization of intracellular free calcium in HEK293 cells.
Physiol Genomics, 5 (1): 11-9.
[PMID:11161002]
26. Mountjoy KG, Robbins LS, Mortrud MT, Cone RD. (1992) The cloning of a family of genes that encode the melanocortin receptors.
Science, 257 (5074): 1248-51.
[PMID:1325670]
27. Ozdeslik RN, Olinski LE, Trieu MM, Oprian DD, Oancea E. (2019) Human nonvisual opsin 3 regulates pigmentation of epidermal melanocytes through functional interaction with melanocortin 1 receptor.
Proc Natl Acad Sci USA, 116 (23): 11508-11517.
[PMID:31097585]
28. Robbins LS, Nadeau JH, Johnson KR, Kelly MA, Roselli-Rehfuss L, Baack E, Mountjoy KG, Cone RD. (1993) Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MSH receptor function.
Cell, 72 (6): 827-34.
[PMID:8458079]
29. Schioth HB, Muceniece R, Wikberg JE, Chhajlani V. (1995) Characterisation of melanocortin receptor subtypes by radioligand binding analysis.
Eur J Pharmacol, 288 (3): 311-317.
[PMID:7774675]
30. Schiöth HB, Muceniece R, Mutulis F, Bouifrouri AA, Mutule I, Wikberg JE. (1999) Further pharmacological characterization of the selective melanocortin 4 receptor antagonist HS014: comparison with SHU9119.
Neuropeptides, 33 (3): 191-6.
[PMID:10657491]
31. Smith AI, Funder JW. (1988) Proopiomelanocortin processing in the pituitary, central nervous system, and peripheral tissues.
Endocr Rev, 9: 159-179.
[PMID:3286233]
32. Star RA, Rajora N, Huang J, Stock RC, Catania A, Lipton JM. (1995) Evidence of autocrine modulation of macrophage nitric oxide synthase by alpha-melanocyte-stimulating hormone.
Proc Natl Acad Sci USA, 92 (17): 8016-20.
[PMID:7544012]
33. Szardenings M, Muceniece R, Mutule I, Mutulis F, Wikberg JE. (2000) New highly specific agonistic peptides for human melanocortin MC(1) receptor.
Peptides, 21 (2): 239-43.
[PMID:10764951]
34. Tan CP, McKee KK, Weinberg DH, MacNeil T, Palyha OC, Feighner SD, Hreniuk DL, Van Der Ploeg LH, MacNeil DJ, Howard AD. (1999) Molecular analysis of a new splice variant of the human melanocortin-1 receptor.
FEBS Lett, 451 (2): 137-41.
[PMID:10371153]
35. Wikberg JE. (1999) Melanocortin receptors: perspectives for novel drugs.
Eur J Pharmacol, 375 (1-3): 295-310.
[PMID:10443584]
36. Yang YK, Dickinson C, Lai YM, Li JY, Gantz I. (2001) Functional properties of an agouti signaling protein variant and characteristics of its cognate radioligand.
Am J Physiol Regul Integr Comp Physiol, 281 (6): R1877-86.
[PMID:11705773]
37. Yang YK, Ollmann MM, Wilson BD, Dickinson C, Yamada T, Barsh GS, Gantz I. (1997) Effects of recombinant agouti-signaling protein on melanocortin action.
Mol Endocrinol, 11 (3): 274-80.
[PMID:9058374]