Fatty liver disease, nonalcoholic, susceptibility to, 1; NAFLD1

Disease ID:1023
Name:Fatty liver disease, nonalcoholic, susceptibility to, 1; NAFLD1
Associated with:2 targets
0 immuno-relevant targets
0 immuno-relevant ligands
Database Links
OMIM: 613282

Targets

NLRP6
Role:  NLRP6 negatively regulates the progression of non-alcoholic fatty liver disease and mtabolic syndrome via modulation of gut bacteria.
References:  1

Ligands

No ligand related data available for Fatty liver disease, nonalcoholic, susceptibility to, 1; NAFLD1

References

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1. Henao-Mejia J, Elinav E, Jin C, Hao L, Mehal WZ, Strowig T, Thaiss CA, Kau AL, Eisenbarth SC, Jurczak MJ et al.. (2012) Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity. Nature, 482 (7384): 179-85. [PMID:22297845]

2. Pashkov V, Huang J, Parameswara VK, Kedzierski W, Kurrasch DM, Tall GG, Esser V, Gerard RD, Uyeda K, Towle HC et al.. (2011) Regulator of G protein signaling (RGS16) inhibits hepatic fatty acid oxidation in a carbohydrate response element-binding protein (ChREBP)-dependent manner. J. Biol. Chem., 286 (17): 15116-25. [PMID:21357625]