Sepsis

Disease ID:1057
Name:Sepsis
Associated with:2 targets
1 immuno-relevant ligand
Synonyms
Septicemia

Targets

TLR1
TLR4

Ligands

Key to terms and symbols Click ligand name to view ligand summary Click column headers to sort
Ligand References Clinical and Disease comments
C5a 1
Immuno Disease Comments: C5a has been shown to impair phagocytic function and migration of peripheral blood neutrophils isolated from critically ill patients.

References

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1. Conway Morris A, Kefala K, Wilkinson TS, Dhaliwal K, Farrell L, Walsh T, Mackenzie SJ, Reid H, Davidson DJ, Haslett C et al.. (2009) C5a mediates peripheral blood neutrophil dysfunction in critically ill patients. Am. J. Respir. Crit. Care Med., 180 (1): 19-28. [PMID:19324972]