Deficiency of IL-36R antagonist

Disease ID:1242
Name:Deficiency of IL-36R antagonist
Associated with:0 targets
0 immuno-relevant targets
1 immuno-relevant ligands
Synonyms
DITRA
Description
The phenotype of this extremely rare autosomal recessive genetic abnormality covers a range of pustular skin syndromes that are variants of generalized pustular psoriasis (GPP). GPP is an acute, episodic, and potentially life-threatening form of psoriasis that presents as repeated episodes of cutaneous pustulosis and plaque development over a wide area of the body.
Database Links
OMIM: 614204
Orphanet: ORPHA404546

Targets

No target related data available for Deficiency of IL-36R antagonist

Ligands

Ligand Approved Immuno References Clinical comments
MAB92
Immuno Disease Comments: MAB92 is an experimental antibody with activity against DITRA type cutaneous pustulitis.