Ovarian cancer

Disease ID:724
Name:Ovarian cancer
Associated with:6 targets
Database Links
Disease Ontology: DOID:2394
OMIM: 167000

Targets

CCR7
References:  1
ADGRB1
References:  2
Mutations:  ADGRB1 is associated with 1 mutation. Click here for details
ADGRB3
References:  2
Mutations:  ADGRB3 is associated with 1 mutation. Click here for details
PKR1
References:  3
Mutations:  PKR1 is associated with 1 mutation. Click here for details
erb-b2 receptor tyrosine kinase 2
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

Ligands

No ligand related data available for Ovarian cancer

References

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1. Cheng S, Han L, Guo J, Yang Q, Zhou J, Yang X. (2014) The essential roles of CCR7 in epithelial-to-mesenchymal transition induced by hypoxia in epithelial ovarian carcinomas. Tumour Biol., 35 (12): 12293-8. [PMID:25168373]

2. Kan Z, Jaiswal BS, Stinson J, Janakiraman V, Bhatt D, Stern HM, Yue P, Haverty PM, Bourgon R, Zheng J, Moorhead M, Chaudhuri S, Tomsho LP, Peters BA, Pujara K, Cordes S, Davis DP, Carlton VE, Yuan W, Li L, Wang W, Eigenbrot C, Kaminker JS, Eberhard DA, Waring P, Schuster SC, Modrusan Z, Zhang Z, Stokoe D, de Sauvage FJ, Faham M, Seshagiri S. (2010) Diverse somatic mutation patterns and pathway alterations in human cancers. Nature, 466 (7308): 869-73. [PMID:20668451]

3. O'Hayre M, Vázquez-Prado J, Kufareva I, Stawiski EW, Handel TM, Seshagiri S, Gutkind JS. (2013) The emerging mutational landscape of G proteins and G-protein-coupled receptors in cancer. Nat. Rev. Cancer, 13 (6): 412-24. [PMID:23640210]