Pilocytic astrocytoma

Disease ID:757
Name:Pilocytic astrocytoma
Associated with:4 targets
Database Links
Disease Ontology: DOID:4851
Orphanet: ORPHA251612

Targets

fibroblast growth factor receptor 1
neurotrophic receptor tyrosine kinase 2
References:  1
B-Raf proto-oncogene, serine/threonine kinase
Raf-1 proto-oncogene, serine/threonine kinase
References:  2

Ligands

No ligand related data available for Pilocytic astrocytoma

References

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1. Jones DT, Hutter B, Jäger N, Korshunov A, Kool M, Warnatz HJ, Zichner T, Lambert SR, Ryzhova M, Quang DA et al.. (2013) Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. Nat. Genet., 45 (8): 927-32. [PMID:23817572]

2. Jones DT, Kocialkowski S, Liu L, Pearson DM, Ichimura K, Collins VP. (2009) Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma. Oncogene, 28 (20): 2119-23. [PMID:19363522]