Sporadic amyotrophic lateral sclerosis

Disease ID:887
Name:Sporadic amyotrophic lateral sclerosis
Associated with:3 targets
Synonyms
SALS
Database Links
Disease Ontology: DOID:332
OMIM: 105400

Targets

nicotinic acetylcholine receptor α3 subunit
References:  1
Mutations:  nicotinic acetylcholine receptor α3 subunit is associated with 2 mutation. Click here for details
nicotinic acetylcholine receptor α4 subunit
References:  1
Mutations:  nicotinic acetylcholine receptor α4 subunit is associated with 9 mutation. Click here for details
nicotinic acetylcholine receptor β4 subunit
References:  1
Mutations:  nicotinic acetylcholine receptor β4 subunit is associated with 3 mutation. Click here for details

Ligands

No ligand related data available for Sporadic amyotrophic lateral sclerosis

References

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1. Sabatelli M, Eusebi F, Al-Chalabi A, Conte A, Madia F, Luigetti M, Mancuso I, Limatola C, Trettel F, Sobrero F et al.. (2009) Rare missense variants of neuronal nicotinic acetylcholine receptor altering receptor function are associated with sporadic amyotrophic lateral sclerosis. Hum. Mol. Genet., 18 (20): 3997-4006. [PMID:19628475]