Pancreatic cancer

Disease ID:982
Name:Pancreatic cancer
Associated with:3 targets
Database Links
Disease Ontology: DOID:1793
OMIM: 260350

Targets

CCR7
References:  3
serine/threonine kinase 11
regulator of G-protein signaling 16
Role:  Pancreatic cancer with lymph node metastasis.
References:  1-2

Ligands

No ligand related data available for Pancreatic cancer

References

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1. Kim JH, Lee JY, Lee KT, Lee JK, Lee KH, Jang KT, Heo JS, Choi SH, Rhee JC. (2010) RGS16 and FosB underexpressed in pancreatic cancer with lymph node metastasis promote tumor progression. Tumour Biol., 31 (5): 541-8. [PMID:20571966]

2. Ocal O, Pashkov V, Kollipara RK, Zolghadri Y, Cruz VH, Hale MA, Heath BR, Artyukhin AB, Christie AL, Tsoulfas P et al.. (2015) A rapid in vivo screen for pancreatic ductal adenocarcinoma therapeutics. Dis Model Mech, 8 (10): 1201-11. [PMID:26438693]

3. Sperveslage J, Frank S, Heneweer C, Egberts J, Schniewind B, Buchholz M, Bergmann F, Giese N, Munding J, Hahn SA et al.. (2012) Lack of CCR7 expression is rate limiting for lymphatic spread of pancreatic ductal adenocarcinoma. Int. J. Cancer, 131 (4): E371-81. [PMID:22020953]