The IUPHAR/BPS Guide to PHARMACOLOGY complete disease list

Immunologically relevant diseases described in GtoPdb.

A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  R  S  T  U  V  W 

Disease name Synonyms Targets Ligands
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Activated PI3K delta syndrome APDS/PASLI | Immunodeficiency 14 | p110 delta activating mutation causing senescent T cells, lymphadenopathy, and immunodeficiency 1 3
Acute lymphocytic leukemia (ALL) Acute lymphoblastic leukemia 3 2
Acute myeloid leukemia Acute myelogenous leukemia 5 4
Adult T-cell leukemia Adult T-cell leukemia/lymphoma | ATLL 0 1
Allergic conjunctivitis 0 8
Allergic rhinitis atopic rhinitis | hay fever | Non-seasonal allergic rhinitis | Perenial allergic rhinitis | pollenosis | seasonal allergic rhinitis 0 13
Allergic urticaria hives 0 9
Alopecia areata circumscribed alopecia 0 2
Anaphylactic shock hypersensitivity reaction disease 0 1
Anaplastic large cell lymphoma 0 1
Ankylosing spondylitis Bekhterev syndrome | Marie-Strumpell disease 0 14
Aspirin exacerbated respiratory diseases 1 1
Asthma 6 77
Atopic dermatitis 2 15
Autoimmune lymphoproliferative syndrome; ALPS 1 1
Autoimmune thrombocytopenic purpura idiopathic thrombocytopenic purpura | Immune thrombocytopenia | Immune thrombocytopenic purpura | ITP | primary immune thrombocytopenia | primary thrombocytopenic purpura 0 4
 
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B-cell chronic lymphocytic leukemia B-CLL | lymphoplasmacytic leukemia | small lymphocytic lymphoma 2 5
B-cell lymphoma 1 3
Bronchospasm bronchial disease 0 1
 
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Chronic granulomatous disease Bridges-Good syndrome | CGD | Congenital dysphagocytosis | Quie syndrome 0 1
Chronic idiopathic urticaria 0 2
Chronic lymphocytic leukemia B-cell chronic lymphocytic leukemia | Chronic lymphatic leukemia | Chronic lymphoid leukemia 4 10
Chronic myelogenous leukemia chronic granulocytic leukemia | CML | myeloid leukemia, chronic 0 1
Chronic obstructive pulmonary disease 0 42
CINCA syndrome Chronic infantile neurological cutaneous articular syndrome 1 1
Colitis 3 5
Crohn's disease Crohn disease | Inflammatory bowel disease 1; IBD1 4 26
Cutaneous T cell lymphoma CTCL | cutaneous T-cell lymphoma 0 1
 
D Back to top
Deficiency of IL-36R antagonist DITRA 0 1
Deficiency of IL-1 receptor antagonist DIRA | Interleukin-1 receptor antagonist deficiency | OMPP | sterile multifocal osteomyelitis with periostitis and pustulosis 0 1
Dermatitis 1 14
Diabetes mellitus, type 2 NIDDM | non-insulin-dependent diabetes mellitus | T2DM 0 1
Duchenne muscular dystrophy 0 2
 
E Back to top
Eosinophilic esophagitis 0 1
 
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Familial cold autoinflammatory syndrome 1; FCAS1 Familial cold urticaria 1 3
Follicular lymphoma 0 1
 
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Gout 1 3
Graft versus host disease graft-versus-host disease | GvHD 2 11
Graves' disease 1 2
 
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Hereditary angioedema HAE 0 2
Hypereosinophilic syndrome, idiopathic; HES Hypereosinophilic syndrome of undetermined significance 1 1
 
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Idiopathic pulmonary fibrosis 1 5
Inflammatory bowel disease 1; IBD1 Inflammatory bowel disease 1 8
Interstitial cystitis 2 1
 
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Juvenile idiopathic arthritis JIA 0 3
Juvenile idiopathic arthritis- systemic systemic juvenile rheumatoid arthritis 0 5
 
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keratoconjunctivitis sicca dry eye disease | KCS | keratitis sicca 0 2
 
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Localized scleroderma circumscribed scleroderma | localised morphea | morphea 0 1
Lupus erythematosus 1 2
Lymphoma, Hodgin, Classic; CHL Hodgkin's lymphoma 1 2
Lymphoma, non-hodgkin, familial Non-Hodgkin lymphoma 4 2
 
M Back to top
Major depressive disorder; MDD 4 1
Mantle cell lymphoma 3 2
Mastocytosis 1 4
Muckle-Wells syndrome CAPS2 | cryopyrin-associated periodic syndrome 2 | MWS | urticaria-deafness-amyloidosis syndrome 1 3
Multicentric Castleman disease Multicentric giant lymph node hyperplasia 0 1
Multiple myeloma plasma cell myeloma 1 5
Multiple sclerosis 9 6
Myasthenia gravis 1 3
Mycosis fungoides Alibert-Bazin syndrome | granuloma fungoides 0 1
Myelodysplastic syndrome 0 2
Myelofibrosis Myelofibrosis with myeloid metaplasia 3 2
Myositis 0 1
 
N Back to top
non-Hodgkin lymphoma 2 7
 
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Osteoarthritis 6 24
Otitis externa swimmer's ear 0 1
 
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Pemphigus 1 2
Polycythemia vera 2 1
Polymyalgia rheumatica 0 1
polyostotic sclerosing histiocytosis Erdheim–Chester disease | Erdheim–Chester syndrome 0 1
Primary progressive multiple sclerosis PPMS | Primary-progressive MS 0 1
Primary sclerosing cholangitis 1 1
Pruritus 0 4
Psoriasis 4 55
Psoriatic arthritis arthritis psoriatica | arthropathic psoriasis 0 16
Pyoderma gangrenosum 0 1
 
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Relapsing-remitting multiple sclerosis Relapsing-remitting MS | RRMS 1 12
Rheumatoid arthritis 19 123
Robinow syndrome, autosomal recessive 1 1
 
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Sarcoidosis Boeck sarcoid | lymphogranulomatosis 0 2
Scleroderma systemic sclerosis 0 4
Sjögren's syndrome Sicca syndrome | Sjögren-Gougerot syndrome 2 6
Systemic lupus erythematosus 6 23
Systemic scleroderma Scleroderma, familial progressive | Systemic sclerosis 1 2
 
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Temporal arteritis Giant cell arteritis 1 2
 
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Ulcerative colitis Inflammatory bowel disease 1; IBD1 3 21
Uveitis 0 6
 
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Vasculitis Angiitis 0 3
 
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Waldenstrom macroglobulinemia lymphoplasmacytic lymphoma | Macroglobulinemia, Waldenstrom, somatic included | Macroglobulinemia, Waldenstrom, susceptibility to, 1 | WM 1 2
WHIM syndrome Warts, Hypogammaglobulinemia, Infections, and Myelokathexis (WHIM) | Warts-Infections-Leukopenia-Myelokatexis (WILM) 1 1