Carboxylases and decarboxylases | Enzymes | IUPHAR/BPS Guide to PHARMACOLOGY

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Carboxylases and decarboxylases

Carboxylases and decarboxylases C

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Subfamilies
Further reading
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Subfamilies

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Carboxylases C
Decarboxylases C

Further reading

* Key recommended reading is highlighted with an asterisk

Adina-Zada A, Zeczycki TN, Attwood PV. (2012) Regulation of the structure and activity of pyruvate carboxylase by acetyl CoA. Arch. Biochem. Biophys., 519 (2): 118-30. [PMID:22120519]

* Bale S, Ealick SE. (2010) Structural biology of S-adenosylmethionine decarboxylase. Amino Acids, 38 (2): 451-60. [PMID:19997761]

Brownsey RW, Boone AN, Elliott JE, Kulpa JE, Lee WM. (2006) Regulation of acetyl-CoA carboxylase. Biochem. Soc. Trans., 34 (Pt 2): 223-7. [PMID:16545081]

* Jitrapakdee S, St Maurice M, Rayment I, Cleland WW, Wallace JC, Attwood PV. (2008) Structure, mechanism and regulation of pyruvate carboxylase. Biochem. J., 413 (3): 369-87. [PMID:18613815]

* Lietzan AD, St Maurice M. (2014) Functionally diverse biotin-dependent enzymes with oxaloacetate decarboxylase activity. Arch. Biochem. Biophys., 544: 75-86. [PMID:24184447]

Molderings GJ, Haenisch B. (2012) Agmatine (decarboxylated L-arginine): physiological role and therapeutic potential. Pharmacol. Ther., 133 (3): 351-65. [PMID:22212617]

* Moya-García AA, Pino-Angeles A, Gil-Redondo R, Morreale A, Sánchez-Jiménez F. (2009) Structural features of mammalian histidine decarboxylase reveal the basis for specific inhibition. Br. J. Pharmacol., 157 (1): 4-13. [PMID:19413567]

Perez-Leal O, Merali S. (2012) Regulation of polyamine metabolism by translational control. Amino Acids, 42 (2-3): 611-7. [PMID:21811825]

Sánchez-Jiménez F, Ruiz-Pérez MV, Urdiales JL, Medina MA. (2013) Pharmacological potential of biogenic amine-polyamine interactions beyond neurotransmission. Br. J. Pharmacol., 170 (1): 4-16. [PMID:23347064]

* Tong L. (2013) Structure and function of biotin-dependent carboxylases. Cell. Mol. Life Sci., 70 (5): 863-91. [PMID:22869039]

* Vance JE, Tasseva G. (2013) Formation and function of phosphatidylserine and phosphatidylethanolamine in mammalian cells. Biochim. Biophys. Acta, 1831 (3): 543-54. [PMID:22960354]

Wu F, Christen P, Gehring H. (2011) A novel approach to inhibit intracellular vitamin B6-dependent enzymes: proof of principle with human and plasmodium ornithine decarboxylase and human histidine decarboxylase. FASEB J., 25 (7): 2109-22. [PMID:21454364]

How to cite this family page

Database page citation:

Carboxylases and decarboxylases. Accessed on 12/07/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=240.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA and CGTP Collaborators (2015) The Concise Guide to PHARMACOLOGY 2015/16: Enzymes. Br J Pharmacol. 172: 6024-6109.