IL-10 receptor family C
Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).
Overview
The IL-10 family of receptors are heterodimeric combinations of family members: IL10RA/IL10RB responds to IL-10; IL20RA/IL20RB responds to IL-19, IL-20 and IL-24; IL22RA1/IL20RB responds to IL-20 and IL-24; IL22RA1/IL10RB responds to IL-22; IFNLR1(previouly known as IL28RA)/IL10RB responds to IFN-λ1, -λ2 and -λ3 (previouly known as IL-29, IL-28A and IL-28B respectively).
Receptors
Complexes
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Interleukin-10 receptor
C
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Interleukin-20 receptor
C
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Interleukin-22α1/20β heteromer
C
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Interleukin-22α1/10β heteromer
C
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Interferon-λ receptor 1
C
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Receptors and Subunits
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Interleukin-22 receptor α2
C
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Interleukin 10 receptor, α subunit
C
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Interleukin 10 receptor, β subunit
C
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Interleukin 20 receptor, α subunit
C
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Interleukin 20 receptor, β subunit
C
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Interleukin 22 receptor, α1 subunit
C
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Interferon-λ receptor subunit 1
C
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Further reading
How to cite this family page
Database page citation:
IL-10 receptor family. Accessed on 18/04/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=311.
Concise Guide to PHARMACOLOGY citation:
Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Catalytic receptors. Br J Pharmacol. 180 Suppl 2:S241-288.
