Sugar phosphatases

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Sugar phosphatases

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Enzymes

PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3) Show summary »« Hide summary More detailed page go icon to follow link

Target Id

2937

Nomenclature

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3

Common abbreviation

PFKFB3

Previous and unofficial names

6-phosphofructo-2-kinase/fructose-2 | iPFK-2 | PFK2

Genes

PFKFB3 (Hs), Pfkfb3 (Mm), Pfkfb3 (Rn)

Ensembl ID

ENSG00000170525 (Hs), ENSMUSG00000026773 (Mm), ENSRNOG00000018911 (Rn)

UniProtKB AC

Q16875 (Hs), O35552 (Rn)

EC number

2.7.1.105
Kinase activity ATP + D-fructose 6-phosphate <=> ADP + beta-D-fructose 2,6-bisphosphate

3.1.3.46
Dephosphorylation activity Beta-D-fructose 2,6-bisphosphate + H(2)O <=> D-fructose 6-phosphate + phosphate

How to cite this family page

Database page citation:

Sugar phosphatases. Accessed on 19/04/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=948.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.