Signal regulatory proteins

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

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Overview

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Signal-regulatory proteins (SIRP) are membrane proteins that are mainly expressed by myeloid cells. SIPRs play essential roles in immune cell and immune response regulation, whilst minimising damage to self [1].

Targets

SIRPA (CD172a) Show summary » More detailed page

References

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How to cite this family page

Database page citation:

Signal regulatory proteins. Accessed on 20/07/2018. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=989.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Buneman OP, Cidlowski JA, Christopoulos A, Davenport AP, Fabbro D, Spedding M, Striessnig J, Davies JA; CGTP Collaborators. (2017) The Concise Guide to PHARMACOLOGY 2017/18: Overview. Br J Pharmacol. 174 Suppl 1: S1-S16.