CP-122288 [Ligand Id: 110] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL159332 (CP-122288) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| 5-HT1B receptor/Serotonin 1b (5-HT1b) receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1898] [GtoPdb: 2] [UniProtKB: P28222] | ||||||||
| GtoPdb | - | - | 7.6 | pIC50 | - | - | - | Naunyn Schmiedebergs Arch Pharmacol (1997) 356: 328-34 [PMID:9303569] |
| ChEMBL | Binding affinity in CHO-K1 cells transfected with human recombinant 5-hydroxytryptamine 1B receptor | B | 7.84 | pIC50 | 14.45 | nM | IC50 | J Med Chem (2001) 44: 681-693 [PMID:11262079] |
| 5-HT1D receptor/Serotonin 1d (5-HT1d) receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1983] [GtoPdb: 3] [UniProtKB: P28221] | ||||||||
| GtoPdb | - | - | 7.7 | pIC50 | - | - | - | Naunyn Schmiedebergs Arch Pharmacol (1997) 356: 328-34 [PMID:9303569] |
| ChEMBL | Binding affinity in CHO-K1 cells transfected with human 5-hydroxytryptamine 1D receptor | B | 8.14 | pIC50 | 7.24 | nM | IC50 | J Med Chem (2001) 44: 681-693 [PMID:11262079] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
