BW 245C [Ligand Id: 1878] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL575504
  • DP1 receptor in Human [GtoPdb: 338] [UniProtKB: Q13258]
  • DP1 receptor in Mouse [GtoPdb: 338] [UniProtKB: P70263]
  • DP1 receptor in Rat [GtoPdb: 338] [UniProtKB: Q9R261]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
DP1 receptor in Human [GtoPdb: 338] [UniProtKB: Q13258]
GtoPdb - - 9.4 pKi - - - Eur J Pharmacol (1999) 377: 101-15 [PMID:10448933];
J Biol Chem (1995) 270: 18910-6 [PMID:7642548];
Br J Pharmacol (1998) 123: 1317-24 [PMID:9579725]
DP1 receptor in Mouse [GtoPdb: 338] [UniProtKB: P70263]
GtoPdb - - 6.6 pKi - - - Br J Pharmacol (1997) 122: 217-24 [PMID:9313928]
DP1 receptor in Rat [GtoPdb: 338] [UniProtKB: Q9R261]
GtoPdb - - 7.8 pKi - - - Eur J Pharmacol (1999) 377: 101-15 [PMID:10448933]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]