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ChEMBL ligand: CHEMBL236025 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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DP1 receptor in Human [GtoPdb: 338] [UniProtKB: Q13258] | ||||||||
GtoPdb | - | - | 6.6 | pKi | - | - | - |
Br J Pharmacol (1998) 123: 1317-24 [PMID:9579725]; Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]; Biochem Pharmacol (2012) 84: 68-75 [PMID:22480736] |
EP1 receptor in Human [GtoPdb: 340] [UniProtKB: P34995] | ||||||||
GtoPdb | - | - | 8 | pKi | - | - | - |
Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]; J Pharm Pharmacol (2002) 54: 539-47 [PMID:11999132] |
EP1 receptor in Mouse [GtoPdb: 340] [UniProtKB: P35375] | ||||||||
GtoPdb | - | - | 7.7 | pKi | - | - | - | Br J Pharmacol (1997) 122: 217-24 [PMID:9313928] |
EP1 receptor in Rat [GtoPdb: 340] [UniProtKB: P70597] | ||||||||
GtoPdb | - | - | 7.9 | pKi | - | - | - | Eur J Pharmacol (1997) 340: 227-41 [PMID:9537820] |
EP2 receptor in Human [GtoPdb: 341] [UniProtKB: P43116] | ||||||||
GtoPdb | - | - | 5.7 | pKi | - | - | - | Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944] |
EP2 receptor in Mouse [GtoPdb: 341] [UniProtKB: Q62053] | ||||||||
GtoPdb | - | - | 5.8 | pKi | - | - | - | Br J Pharmacol (1997) 122: 217-24 [PMID:9313928] |
EP2 receptor in Rat [GtoPdb: 341] [UniProtKB: Q62928] | ||||||||
GtoPdb | - | - | 5.9 | pKi | - | - | - | Eur J Pharmacol (1997) 340: 227-41 [PMID:9537820] |
EP3 receptor in Human [GtoPdb: 342] [UniProtKB: P43115] | ||||||||
GtoPdb | - | - | 6.68 | pKi | 208 | nM | Ki | Biochem Pharmacol (2012) 84: 68-75 [PMID:22480736] |
GtoPdb | - | - | 7.25 | pKi | 56 | nM | Ki | Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944] |
EP3 receptor in Mouse [GtoPdb: 342] [UniProtKB: P30557] | ||||||||
GtoPdb | - | - | 7.66 | pKi | 22 | nM | Ki | Br J Pharmacol (1997) 122: 217-24 [PMID:9313928] |
EP3 receptor in Rat [GtoPdb: 342] [UniProtKB: P34980] | ||||||||
GtoPdb | - | - | 7.33 | pKi | 47 | nM | Ki | Eur J Pharmacol (1997) 340: 227-41 [PMID:9537820] |
GtoPdb | - | - | 9.2 | pEC50 | 0.63 | nM | EC50 | Eur J Pharmacol (1997) 340: 227-41 [PMID:9537820] |
EP4 receptor in Human [GtoPdb: 343] [UniProtKB: P35408] | ||||||||
GtoPdb | - | - | 6.68 | pKi | 210 | nM | Ki |
Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]; Br J Pharmacol (2000) 130: 1919-1926 [PMID:10952683]; Biochem Pharmacol (2012) 84: 68-75 [PMID:22480736] |
GtoPdb | - | - | 6.4 | pEC50 | 400 | nM | EC50 | Biochem Pharmacol (2012) 84: 68-75 [PMID:22480736] |
EP4 receptor in Mouse [GtoPdb: 343] [UniProtKB: P32240] | ||||||||
GtoPdb | - | - | 5.6 | pKi | - | - | - | Br J Pharmacol (1997) 122: 217-24 [PMID:9313928] |
FP receptor in Human [GtoPdb: 344] [UniProtKB: P43088] | ||||||||
GtoPdb | - | - | 6.2 | pKi | - | - | - | Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944] |
IP receptor in Human [GtoPdb: 345] [UniProtKB: P43119] | ||||||||
GtoPdb | - | - | 8 | pKi | - | - | - |
Br J Pharmacol (2006) 148: 326-39 [PMID:16604093]; Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944] |
IP receptor in Mouse [GtoPdb: 345] [UniProtKB: P43252] | ||||||||
GtoPdb | - | - | 8 | pKi | - | - | - | Br J Pharmacol (1997) 122: 217-24 [PMID:9313928] |
TP receptor in Human [GtoPdb: 346] [UniProtKB: P21731] | ||||||||
GtoPdb | - | - | 5.2 | pKi | - | - | - | Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]