cicaprost [Ligand Id: 1917] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL160629 (Cicaprost) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| EP1 receptor in Human [GtoPdb: 340] [UniProtKB: P34995] | ||||||||
| GtoPdb | - | - | 5.9 | pKi | - | - | - | Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944] |
| EP2 receptor in Mouse [GtoPdb: 341] [UniProtKB: Q62053] | ||||||||
| GtoPdb | - | - | 5.9 | pKi | - | - | - | Br J Pharmacol (1997) 122: 217-24 [PMID:9313928] |
| EP3 receptor in Human [GtoPdb: 342] [UniProtKB: P43115] | ||||||||
| GtoPdb | - | - | 6.59 | pKi | 255 | nM | Ki | Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944] |
| EP3 receptor in Mouse [GtoPdb: 342] [UniProtKB: P30557] | ||||||||
| GtoPdb | - | - | 6.77 | pKi | 170 | nM | Ki | Br J Pharmacol (1997) 122: 217-24 [PMID:9313928] |
| EP4 receptor in Human [GtoPdb: 343] [UniProtKB: P35408] | ||||||||
| GtoPdb | - | - | 7.4 | pKi | - | - | - | Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944] |
| IP receptor in Human [GtoPdb: 345] [UniProtKB: P43119] | ||||||||
| GtoPdb | - | - | 7.8 | pKi | - | - | - | Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944] |
| IP receptor in Mouse [GtoPdb: 345] [UniProtKB: P43252] | ||||||||
| GtoPdb | - | - | 8 | pKi | - | - | - | Br J Pharmacol (1997) 122: 217-24 [PMID:9313928] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
