vapreotide [Ligand Id: 2054] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL264186
  • SST2 receptor in Human [GtoPdb: 356] [UniProtKB: P30874]
  • SST2 receptor in Mouse [GtoPdb: 356] [UniProtKB: P30875]
  • SST2 receptor in Rat [GtoPdb: 356] [UniProtKB: P30680]
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  • SST3 receptor in Human [GtoPdb: 357] [UniProtKB: P32745]
  • SST3 receptor in Rat [GtoPdb: 357] [UniProtKB: P30936]
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  • SST5 receptor in Human [GtoPdb: 359] [UniProtKB: P35346]
  • SST5 receptor in Rat [GtoPdb: 359] [UniProtKB: P30938]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
SST2 receptor in Human [GtoPdb: 356] [UniProtKB: P30874]
GtoPdb - - 10.1 pKi - - - Metab Clin Exp (1996) 45: 17-20 [PMID:8769372];
Endocrinology (1994) 135: 2814-7 [PMID:7988476]
SST2 receptor in Mouse [GtoPdb: 356] [UniProtKB: P30875]
GtoPdb - - 9.2 pKi - - - Rev Physiol Biochem Pharmacol (1998) 133: 55-108 [PMID:9600011]
SST2 receptor in Rat [GtoPdb: 356] [UniProtKB: P30680]
GtoPdb - - 9.1 pKi - - - Rev Physiol Biochem Pharmacol (1998) 133: 55-108 [PMID:9600011]
SST3 receptor in Human [GtoPdb: 357] [UniProtKB: P32745]
GtoPdb - - 7.9 pKi - - - Metab Clin Exp (1996) 45: 17-20 [PMID:8769372];
Naunyn Schmiedebergs Arch Pharmacol (1998) 357: 483-9 [PMID:9650799];
Endocrinology (1994) 135: 2814-7 [PMID:7988476]
SST3 receptor in Rat [GtoPdb: 357] [UniProtKB: P30936]
GtoPdb - - 7.1 pKi - - - Rev Physiol Biochem Pharmacol (1998) 133: 55-108 [PMID:9600011]
SST5 receptor in Human [GtoPdb: 359] [UniProtKB: P35346]
GtoPdb - - 9.2 pKi - - - Metab Clin Exp (1996) 45: 17-20 [PMID:8769372];
Naunyn Schmiedebergs Arch Pharmacol (1998) 357: 483-9 [PMID:9650799];
Naunyn Schmiedebergs Arch Pharmacol (1999) 360: 488-99 [PMID:10598788];
Rev Physiol Biochem Pharmacol (1998) 133: 55-108 [PMID:9600011];
Endocrinology (1994) 135: 2814-7 [PMID:7988476];
Eur J Pharmacol (1998) 348: 311-20 [PMID:9652348]
SST5 receptor in Rat [GtoPdb: 359] [UniProtKB: P30938]
GtoPdb - - 8.2 pKi - - - Rev Physiol Biochem Pharmacol (1998) 133: 55-108 [PMID:9600011]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]