ChEMBL ligand: CHEMBL339427 (D-tubocurarine, Tubocurarine, Tubocurarine cation, Tubocurarine ion)
Multidrug and toxin extrusion/Multidrug and toxin extrusion protein 1 in Human [ChEMBL: CHEMBL1743126] [GtoPdb: 1216] [UniProtKB: Q96FL8] There should be some charts here, you may need to enable JavaScript!
MATE2/Multidrug and toxin extrusion protein 2 in Human [ChEMBL: CHEMBL1743127] [GtoPdb: 1217] [UniProtKB: Q86VL8] There should be some charts here, you may need to enable JavaScript!
Nicotinic acetylcholine receptor alpha 5 subunit in Musca domestica [ChEMBL: CHEMBL2366408] [UniProtKB: A9XFY4] There should be some charts here, you may need to enable JavaScript!
Organic cation transporter 2/Solute carrier family 22 member 2 in Human [ChEMBL: CHEMBL1743122] [GtoPdb: 1020] [UniProtKB: O15244] There should be some charts here, you may need to enable JavaScript!
5-HT3AB in Human [GtoPdb: 378] There should be some charts here, you may need to enable JavaScript!
5-HT3A in Human [GtoPdb: 379] 5-HT3A in Mouse [GtoPdb: 379] There should be some charts here, you may need to enable JavaScript!
KCa2.1 in Human [GtoPdb: 381] [UniProtKB: Q92952] There should be some charts here, you may need to enable JavaScript!
KCa2.2 in Human [GtoPdb: 382] [UniProtKB: Q9H2S1] KCa2.2 in Rat [GtoPdb: 382] [UniProtKB: P70604] There should be some charts here, you may need to enable JavaScript!
KCa2.3 in Human [GtoPdb: 383] [UniProtKB: Q9UGI6] There should be some charts here, you may need to enable JavaScript!
ZAC in Human [GtoPdb: 587] [UniProtKB: Q401N2] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Multidrug and toxin extrusion/Multidrug and toxin extrusion protein 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1743126] [GtoPdb: 1216] [UniProtKB: Q96FL8]
ChEMBL	Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	B	5.03	pIC50	9400	nM	IC50	J Med Chem (2013) 56: 781-795 [PMID:23241029]
MATE2/Multidrug and toxin extrusion protein 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1743127] [GtoPdb: 1217] [UniProtKB: Q86VL8]
ChEMBL	Inhibition of human MATE2K-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay	B	4.26	pIC50	55500	nM	IC50	J Med Chem (2013) 56: 781-795 [PMID:23241029]
Nicotinic acetylcholine receptor alpha 5 subunit in Musca domestica (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2366408] [UniProtKB: A9XFY4]
ChEMBL	Displacement of [3H]alpha-bungarotoxin from nAChR in Musca domestica (house fly) head membrane after 60 min by scintillation counting	B	5.73	pKi	1880	nM	Ki	J Pestic Sci (1992) 17: 231-236
Organic cation transporter 2/Solute carrier family 22 member 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1743122] [GtoPdb: 1020] [UniProtKB: O15244]
ChEMBL	Inhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay	B	4.1	pIC50	78800	nM	IC50	J Med Chem (2013) 56: 781-795 [PMID:23241029]
5-HT3AB in Human [GtoPdb: 378]
GtoPdb	-	-	4.5	pKi	-	-	-	Neuropharmacology (2001) 41: 282-4 [PMID:11489465]
5-HT3A in Human [GtoPdb: 379]
GtoPdb	-	-	4.8	pKi	-	-	-	Neuropharmacology (2001) 41: 282-4 [PMID:11489465]; Br J Pharmacol (1996) 118: 1237-45 [PMID:8818349]
5-HT3A in Mouse [GtoPdb: 379]
GtoPdb	-	-	7.1	pKi	-	-	-	J Neurochem (1995) 65: 104-10 [PMID:7790853]; Neuropharmacology (1998) 37: 251-7 [PMID:9680250]
KCa2.1 in Human [GtoPdb: 381] [UniProtKB: Q92952]
GtoPdb	-	-	4.6	pIC50	25000	nM	IC50	Science (1996) 273: 1709-14 [PMID:8781233]; Br J Pharmacol (2000) 129: 627-30 [PMID:10683185]; Br J Pharmacol (2000) 129: 991-9 [PMID:10696100]
KCa2.2 in Human [GtoPdb: 382] [UniProtKB: Q9H2S1]
GtoPdb	-	-	5.7	pIC50	-	-	-	FEBS Lett (2000) 469: 196-202 [PMID:10713270]
KCa2.2 in Rat [GtoPdb: 382] [UniProtKB: P70604]
GtoPdb	-	-	5.6	pIC50	-	-	-	Science (1996) 273: 1709-14 [PMID:8781233]; Br J Pharmacol (2000) 129: 991-9 [PMID:10696100]; J Biol Chem (1997) 272: 23195-200 [PMID:9287325]
KCa2.3 in Human [GtoPdb: 383] [UniProtKB: Q9UGI6]
GtoPdb	-	-	4.5	pIC50	-	-	-	Neuropharmacology (2001) 40: 772-83 [PMID:11369031]; Mol Pharmacol (2004) 65: 788-801 [PMID:14978258]
ZAC in Human [GtoPdb: 587] [UniProtKB: Q401N2]
GtoPdb	-	-	5.2	pIC50	6300	nM	IC50	J Biol Chem (2003) 278: 712-7 [PMID:12381728]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]