ivermectin [Ligand Id: 2373] activity data from GtoPdb

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  • Glycine Receptor (All subtypes) in Human [GtoPdb: 428]
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  • nicotinic acetylcholine receptor α7 subunit in Human [GtoPdb: 468] [UniProtKB: P36544]
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  • P2X4 in Rat [GtoPdb: 481] [UniProtKB: P51577]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Glycine Receptor (All subtypes) in Human [GtoPdb: 428]
GtoPdb - - 6.4 pEC50 - - - J Biol Chem (2001) 276: 12556-64 [PMID:11278873]
nicotinic acetylcholine receptor α7 subunit in Human [GtoPdb: 468] [UniProtKB: P36544]
GtoPdb - - 5.1 pEC50 9000 nM EC50 Mol Pharmacol (1998) 53: 283-94 [PMID:9463487]
P2X4 in Rat [GtoPdb: 481] [UniProtKB: P51577]
GtoPdb - - 6.6 pEC50 ~250 nM EC50 J Neurosci (1999) 19: 7289-99 [PMID:10460235]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.