gentamicin [Ligand Id: 2427] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL329592
  • TRPA1 in Mouse [GtoPdb: 485] [UniProtKB: Q8BLA8]
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  • TRPV5 in Human [GtoPdb: 511] [UniProtKB: Q9NQA5]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
TRPA1 in Mouse [GtoPdb: 485] [UniProtKB: Q8BLA8]
GtoPdb - - 5.2 pIC50 - - - J Neurosci (2005) 25: 4052-61 [PMID:15843607]
TRPV5 in Human [GtoPdb: 511] [UniProtKB: Q9NQA5]
GtoPdb - - 6 pIC50 1000 nM IC50 J Am Soc Nephrol (2022) 33: 547-564 [PMID:35022312]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]