calcipotriol [Ligand Id: 2778] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL1200666 (Calcipotriene, Calcipotriene hydrate, Calcipotriene monohydrate, Calcipotriol, Calcipotriol anhydrous, Calcipotriol hydrate, Calcipotriol monohydrate, Calciptriol, Dovobet, Dovonex, Enstilar, MC 903, MC-903, PRI-2201, Sorilux, Xamiol) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Vitamin D receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1977] [GtoPdb: 605] [UniProtKB: P11473] | ||||||||
| GtoPdb | - | - | 9.3 | pKd | - | - | - | J Bone Miner Res (1994) 9: 1277-88 [PMID:7976510] |
| ChEMBL | Binding affinity to VDR receptor | B | 9.51 | pKd | 0.31 | nM | Kd | J Med Chem (2001) 44: 281-297 [PMID:11462969] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
