compound 8 [Brinkman et al., 1996] [Ligand Id: 3066] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL83546
  • squalene synthase /Squalene synthetase in Rat [ChEMBL: CHEMBL3815] [GtoPdb: 645] [UniProtKB: Q02769]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
squalene synthase /Squalene synthetase in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3815] [GtoPdb: 645] [UniProtKB: Q02769]
ChEMBL Compound was tested for inhibitory activity against squalene synthase using rat liver microsomal assay B 8.05 pIC50 9 nM IC50 Bioorg. Med. Chem. Lett. (1996) 6: 2491-2494
GtoPdb Compound was tested for inhibitory activity against squalene synthase using rat liver microsomal assay - 8.05 pIC50 9 nM IC50 Bioorg. Med. Chem. Lett. (1996) 6: 2491-2494

ChEMBL data shown on this page come from version 25:

A.P. Bento, A. Gaulton, A. Hersey, et al. (2014). The ChEMBL bioactivity database: an update. Nucl. Acids Res. Database Issue. 42 D1083-D1090. [PMID:24214965]