donitriptan [Ligand Id: 39] activity data from GtoPdb and ChEMBL
Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
| ChEMBL ligand: CHEMBL1742428 (Donitriptan, Donitriptan hydrochloride, F-11356) |
|---|
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| 5-HT1A receptor in Human [GtoPdb: 1] [UniProtKB: P08908] | ||||||||
| GtoPdb | - | - | 7.6 | pKi | - | - | - | J Pharmacol Exp Ther (1999) 290: 83-95 [PMID:10381763] |
| 5-HT1B receptor in Human [GtoPdb: 2] [UniProtKB: P28222] | ||||||||
| GtoPdb | - | - | 9.4 | pKi | - | - | - | J Pharmacol Exp Ther (1999) 290: 83-95 [PMID:10381763] |
| 5-HT1B receptor in Rat [GtoPdb: 2] [UniProtKB: P28564] | ||||||||
| GtoPdb | - | - | 9.7 | pKi | - | - | - | J Pharmacol Exp Ther (1999) 290: 83-95 [PMID:10381763] |
| 5-HT1D receptor in Human [GtoPdb: 3] [UniProtKB: P28221] | ||||||||
| GtoPdb | - | - | 9.3 | pKi | - | - | - | J Pharmacol Exp Ther (1999) 290: 83-95 [PMID:10381763] |
| 5-HT1D receptor in Rat [GtoPdb: 3] [UniProtKB: P28565] | ||||||||
| GtoPdb | - | - | 9.6 | pKi | - | - | - | J Pharmacol Exp Ther (1999) 290: 83-95 [PMID:10381763] |
| 5-ht1e receptor in Human [GtoPdb: 4] [UniProtKB: P28566] | ||||||||
| GtoPdb | - | - | 5.9 | pKi | - | - | - | J Pharmacol Exp Ther (1999) 290: 83-95 [PMID:10381763] |
| 5-HT1F receptor in Human [GtoPdb: 5] [UniProtKB: P30939] | ||||||||
| GtoPdb | - | - | 5.5 | pKi | - | - | - | J Pharmacol Exp Ther (1999) 290: 83-95 [PMID:10381763] |
| 5-HT2A receptor in Human [GtoPdb: 6] [UniProtKB: P28223] | ||||||||
| GtoPdb | - | - | 6.7 | pKi | - | - | - | J Pharmacol Exp Ther (1999) 290: 83-95 [PMID:10381763] |
| 5-HT5A receptor in Human [GtoPdb: 10] [UniProtKB: P47898] | ||||||||
| GtoPdb | - | - | 6.1 | pKi | - | - | - | J Pharmacol Exp Ther (1999) 290: 83-95 [PMID:10381763] |
| 5-HT6 receptor in Human [GtoPdb: 11] [UniProtKB: P50406] | ||||||||
| GtoPdb | - | - | 5.6 | pKi | - | - | - | J Pharmacol Exp Ther (1999) 290: 83-95 [PMID:10381763] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
