4-AMBA [Ligand Id: 4702] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL328875 (4-Aminomethyl-Benzoic Acid, 4-(Aminomethyl)Benzoic Acid, Aminomethylbenzoic acid)
  • Peptide transporter 1 in Human [GtoPdb: 984] [UniProtKB: P46059]
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  • Peptide transporter 2 in Human [GtoPdb: 985] [UniProtKB: Q16348]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Peptide transporter 1 in Human [GtoPdb: 984] [UniProtKB: P46059]
GtoPdb - - 2.3 pKi - - Ki J Nutr (2005) 135: 1491-5 [PMID:15930458];
J Physiol (Lond.) (1998) 512 ( Pt 3): 629-34 [PMID:9882198];
J Pharmacol Exp Ther (2010) 332: 220-8 [PMID:19789362]
Peptide transporter 2 in Human [GtoPdb: 985] [UniProtKB: Q16348]
GtoPdb - - 2.5 pKi - - - Amino Acids (2006) 31: 137-56 [PMID:16868651];
J Biol Chem (2002) 277: 7287-92 [PMID:11751927]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]