ChEMBL ligand: CHEMBL184 (Aciclovir, Aciclovirum, Acycloguanosine, Acyclovir, Avaclyr, Avert, Aviral, Clearsore, Cyclovir, Cymex ultra, Duvimex, Gerpevir, Herpetad, Lipsore, Lypsyl, Novirus, NSC-645011, NSC-758477, Ranovir, Sitavig, Soothelip, Soraway, Viralief, Virasorb, Virovir 200, Virovir 400, Virovir 800, Zovirax)
Purine nucleoside phosphorylase in Mycobacterium tuberculosis [ChEMBL: CHEMBL1169594] [UniProtKB: P9WP01] purine nucleoside phosphorylase/Purine nucleoside phosphorylase in Human [ChEMBL: CHEMBL4338] [GtoPdb: 2841] [UniProtKB: P00491] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Purine nucleoside phosphorylase in Mycobacterium tuberculosis (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1169594] [UniProtKB: P9WP01]
ChEMBL	Binding affinity to Mycobacterium tuberculosis purine nucleoside phosphorylase by spectrophotometric analysis	B	4.9	pKd	12589.25	nM	Kd	Bioorg Med Chem (2010) 18: 4769-4774 [PMID:20570524]
purine nucleoside phosphorylase/Purine nucleoside phosphorylase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4338] [GtoPdb: 2841] [UniProtKB: P00491]
ChEMBL	Inhibition of human PNP	B	4.04	pKi	91000	nM	Ki	Medchemcomm (2018) 9: 1983-1993 [PMID:30627387]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]