ChEMBL ligand: CHEMBL32800 (Airum, Berodual, Berodual n, Berotec, Berotec 100, Berotec 200, Berotec [as hydrobromide], Dosberotec, Duovent, Fenoterol, Fenoterol hbr, Fenoterol hydrobromide, NSC-757811, Partusisten, TH-1165, TH 1165A, TH-1165A, TH 1165A [AS HYDROBROMIDE SALT], TH 1165A FREE BASE, TH-1165A FREE BASE)
β2-adrenoceptor/Beta-2 adrenergic receptor in Human [ChEMBL: CHEMBL210] [GtoPdb: 29] [UniProtKB: P07550] Beta-2 adrenergic receptor in Guinea pig [ChEMBL: CHEMBL5414] [UniProtKB: Q8K4Z4] There should be some charts here, you may need to enable JavaScript!
β1-adrenoceptor in Human [GtoPdb: 28] [UniProtKB: P08588] There should be some charts here, you may need to enable JavaScript!
β3-adrenoceptor in Human [GtoPdb: 30] [UniProtKB: P13945] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
β2-adrenoceptor/Beta-2 adrenergic receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL210] [GtoPdb: 29] [UniProtKB: P07550]
ChEMBL	Binding affinity to N-terminal FLAG-tagged C-terminal His-10-tagged human beta2 adrenoceptor expressed in insect Sf9 cells by surface plasmon resonance analysis	B	6.86	pKd	139	nM	Kd	ACS Med Chem Lett (2013) 4: 1005-1010 [PMID:24454993]
ChEMBL	Binding affinity to beta-2 adrenergic receptor (unknown origin) at 1 to 10000 nM	B	7	pKd	100	nM	Kd	Bioorg Med Chem Lett (2013) 23: 5376-5381 [PMID:23954364]
ChEMBL	Displacement of [3H]-CGP12177 from human recombinant beta2 adrenoceptor expressed in HEK293 cells after 1 hr by scintillation counting analysis	B	6.9	pKi	126	nM	Ki	ACS Med Chem Lett (2013) 4: 1005-1010 [PMID:24454993]
GtoPdb	-	-	7	pKi	-	-	-	Br J Pharmacol (2010) 160: 1048-61 [PMID:20590599]; ACS Med Chem Lett (2013) 4: 1005-1010 [PMID:24454993]; Br J Pharmacol (2022) 179: 4692-4708 [PMID:35732075]; Mol Pharmacol (2015) 87: 103-20 [PMID:25324048]
GtoPdb	-	-	8.9	pEC50	-	-	-	Br J Pharmacol (2010) 160: 1048-61 [PMID:20590599]; Br J Pharmacol (2022) 179: 4692-4708 [PMID:35732075]
Beta-2 adrenergic receptor in Guinea pig (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5414] [UniProtKB: Q8K4Z4]
ChEMBL	In vitro inhibitory concentration Beta-2 adrenergic receptor in Guinea pig trachea	B	7.22	pIC50	60	nM	IC50	Bioorg Med Chem Lett (2003) 13: 2687-2692 [PMID:12873495]
ChEMBL	Agonist activity at adrenergic beta-2 receptor in guinea pig tracheal rings assessed as myorelaxing activity on carbachol-induced contraction in presence of 1H-[1,2,4]oxadiazolo-[4,3-a]quinoxalin-1-one	F	7.72	pEC50	19	nM	EC50	J Med Chem (2007) 50: 5003-5011 [PMID:17845020]
ChEMBL	Agonist activity at adrenergic beta-2 receptor in guinea pig tracheal rings assessed as myorelaxing activity on carbachol-induced contraction	F	7.74	pEC50	18	nM	EC50	J Med Chem (2007) 50: 5003-5011 [PMID:17845020]
β1-adrenoceptor in Human [GtoPdb: 28] [UniProtKB: P08588]
GtoPdb	-	-	5	pKi	-	-	-	Br J Pharmacol (2010) 160: 1048-61 [PMID:20590599]
GtoPdb	-	-	7.5	pEC50	-	-	-	Br J Pharmacol (2010) 160: 1048-61 [PMID:20590599]
β3-adrenoceptor in Human [GtoPdb: 30] [UniProtKB: P13945]
GtoPdb	-	-	5.4	pKi	-	-	-	Br J Pharmacol (2010) 160: 1048-61 [PMID:20590599]
GtoPdb	-	-	7.6	pEC50	-	-	-	Br J Pharmacol (2010) 160: 1048-61 [PMID:20590599]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]