ChEMBL ligand: CHEMBL273653
coagulation factor X/Coagulation factor X in Human [ChEMBL: CHEMBL244] [GtoPdb: 2359] [UniProtKB: P00742] There should be some charts here, you may need to enable JavaScript!
coagulation factor XI/Coagulation factor XI in Human [ChEMBL: CHEMBL2820] [GtoPdb: 2360] [UniProtKB: P03951] There should be some charts here, you may need to enable JavaScript!
coagulation factor II, thrombin/Thrombin in Human [ChEMBL: CHEMBL204] [GtoPdb: 2362] [UniProtKB: P00734] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
coagulation factor X/Coagulation factor X in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL244] [GtoPdb: 2359] [UniProtKB: P00742]
ChEMBL	Inhibition of factor 10a	B	5.72	pIC50	1900	nM	IC50	J Med Chem (2006) 49: 7781-7791 [PMID:17181160]
ChEMBL	Inhibition of human factor 10a	B	5.72	pIC50	1900	nM	IC50	Bioorg Med Chem (2008) 16: 1562-1595 [PMID:18053726]
coagulation factor XI/Coagulation factor XI in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2820] [GtoPdb: 2360] [UniProtKB: P03951]
GtoPdb	-	-	7.5	pIC50	30	nM	IC50	Bioorg Med Chem (2008) 16: 1562-95 [PMID:18053726]
ChEMBL	Inhibition of factor 11a	B	7.52	pIC50	30	nM	IC50	J Med Chem (2006) 49: 7781-7791 [PMID:17181160]
ChEMBL	Inhibition of human factor 11a	B	7.52	pIC50	30	nM	IC50	Bioorg Med Chem (2008) 16: 1562-1595 [PMID:18053726]
coagulation factor II, thrombin/Thrombin in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL204] [GtoPdb: 2362] [UniProtKB: P00734]
ChEMBL	Inhibition of thrombin	B	5.96	pIC50	1100	nM	IC50	J Med Chem (2006) 49: 7781-7791 [PMID:17181160]
ChEMBL	Inhibition of human alpha-thrombin	B	5.96	pIC50	1100	nM	IC50	Bioorg Med Chem (2008) 16: 1562-1595 [PMID:18053726]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]