efalizumab [Ligand Id: 6593] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL1201575 (ANTI-CD11A, Efalizumab, HU-1124, HU1124, Raptiva) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| integrin, alpha L subunit (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) in Human [GtoPdb: 2451] [UniProtKB: P20701] | ||||||||
| GtoPdb | Binding of humanized MHM24 to human CD11a on Jurkat cells. | - | 11.4 | pKd | 0 | nM | Kd | US6703018. Method of treatment using humanized anti-CD11a antibodies. (2004) |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
