befloxatone [Ligand Id: 6637] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL416578 (Befloxatone) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Monoamine oxidase A in Bovine (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3254] [UniProtKB: P21398] | ||||||||
| ChEMBL | Inhibition of bovine brain MAOA using kynuramine as a substrate after 30 mins by spectrofluorometric method | B | 8.6 | pKi | 2.5 | nM | Ki | J Med Chem (2011) 54: 8228-8232 [PMID:22017497] |
| Monoamine oxidase B in Bovine (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2756] [UniProtKB: P56560] | ||||||||
| ChEMBL | Inhibition of bovine brain MAOB using kynuramine as a substrate after 30 mins by spectrofluorometric method | B | 6.66 | pKi | 220 | nM | Ki | J Med Chem (2011) 54: 8228-8232 [PMID:22017497] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
