ChEMBL ligand: CHEMBL247920 (BMS-309403)
fatty acid binding protein 4/Fatty acid binding protein adipocyte in Human [ChEMBL: CHEMBL2083] [GtoPdb: 2534] [UniProtKB: P15090] There should be some charts here, you may need to enable JavaScript!
fatty acid binding protein 4/Fatty acid-binding protein, adipocyte in Rat [ChEMBL: CHEMBL2021755] [GtoPdb: 2534] [UniProtKB: P70623] There should be some charts here, you may need to enable JavaScript!
fatty acid binding protein 5/Fatty acid binding protein epidermal in Human [ChEMBL: CHEMBL3674] [GtoPdb: 2535] [UniProtKB: Q01469] There should be some charts here, you may need to enable JavaScript!
fatty acid binding protein 3/Fatty acid binding protein muscle in Human [ChEMBL: CHEMBL3344] [GtoPdb: 2533] [UniProtKB: P05413] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
fatty acid binding protein 4/Fatty acid binding protein adipocyte in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2083] [GtoPdb: 2534] [UniProtKB: P15090]
ChEMBL	Direct binding to His6-tagged FABP4 (unknown origin) expressed in Escherichia coli BL21(DE3) cells by isothermal titration calorimetry	B	5.69	pKd	2050	nM	Kd	Bioorg Med Chem (2016) 24: 4310-4317 [PMID:27460668]
ChEMBL	Binding affinity at recombinant human 6His-tagged FABP4 expressed in Escherichia coli BL21 DE3 by isothermal titration calorimetry	B	6.6	pKd	252.7	nM	Kd	J Med Chem (2020) 63: 4090-4106 [PMID:32202425]
ChEMBL	Displacement of 1,8-ANS from recombinant human 6His-tagged FABP4 expressed in Escherichia coli BL21 DE3 incubated for 15 mins followed by 1,8-ANS addition and measured after 3 mins by fluorescence based assay	B	6.6	pKi	253.4	nM	Ki	J Med Chem (2020) 63: 4090-4106 [PMID:32202425]
ChEMBL	Displacement of 1,8-ANS from His6-tagged FABP4 (unknown origin) expressed in Escherichia coli BL21(DE3) cells by fluorescence assay	B	6.66	pKi	220	nM	Ki	Bioorg Med Chem (2016) 24: 4310-4317 [PMID:27460668]
ChEMBL	Binding affinity to His-tagged human recombinant FABP4 expressed in Escherichia coli BL21 (DE3) by fluorescence assay	B	6.8	pKi	160	nM	Ki	ACS Med Chem Lett (2016) 7: 435-439 [PMID:27096055]
ChEMBL	Displacement of fluorescent 1-anilinonapthalene 8-sulfonic acid from human a-FABP by fluorescence spectrophotometry	B	7.82	pKi	15	nM	Ki	Bioorg Med Chem Lett (2011) 21: 2949-2952 [PMID:21481589]
ChEMBL	Displacement of [3H]2,3-bis[(2,4-dichlorobenzyl)oxy]benzoic acid from aFABP	B	8.13	pKi	7.4	nM	Ki	Bioorg Med Chem Lett (2007) 17: 3511-3515 [PMID:17502136]
ChEMBL	Displacement of 1,8-ANS from aFABP by fluorescence based-assay	B	8.7	pKi	<2	nM	Ki	Bioorg Med Chem Lett (2007) 17: 3511-3515 [PMID:17502136]
ChEMBL	Inhibition of human FABP4 by 8-anilino-1-naphthalenesulfonic acid based fluorescence displacement assay	B	6.66	pIC50	221	nM	IC50	Bioorg Med Chem Lett (2013) 23: 1662-1666 [PMID:23395658]
fatty acid binding protein 4/Fatty acid-binding protein, adipocyte in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2021755] [GtoPdb: 2534] [UniProtKB: P70623]
ChEMBL	Inhibition of rat ap2 by fluorescent 1,8-anilino-8-naphthalene sulfonate assay	B	7.54	pKi	29	nM	Ki	Eur J Med Chem (2012) 52: 70-81 [PMID:22483089]
fatty acid binding protein 5/Fatty acid binding protein epidermal in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3674] [GtoPdb: 2535] [UniProtKB: Q01469]
ChEMBL	Displacement of 1,8-ANS from recombinant human 6His-tagged FABP5 expressed in Escherichia coli BL21 DE3 incubated for 15 mins followed by 1,8-ANS addition and measured after 3 mins by fluorescence based assay	B	5.03	pKi	9240	nM	Ki	J Med Chem (2020) 63: 4090-4106 [PMID:32202425]
ChEMBL	Displacement of 1,8-ANS from eFABP by fluorescence based-assay	B	6.46	pKi	350	nM	Ki	Bioorg Med Chem Lett (2007) 17: 3511-3515 [PMID:17502136]
fatty acid binding protein 3/Fatty acid binding protein muscle in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3344] [GtoPdb: 2533] [UniProtKB: P05413]
ChEMBL	Displacement of 1,8-ANS from recombinant human 6His-tagged FABP3 expressed in Escherichia coli BL21 DE3 incubated for 15 mins followed by 1,8-ANS addition and measured after 3 mins by fluorescence based assay	B	5.13	pKi	7450	nM	Ki	J Med Chem (2020) 63: 4090-4106 [PMID:32202425]
ChEMBL	Displacement of fluorescent 1-anilinonapthalene 8-sulfonic acid from human h-FABP by fluorescence spectrophotometry	B	5.46	pKi	3470	nM	Ki	Bioorg Med Chem Lett (2011) 21: 2949-2952 [PMID:21481589]
ChEMBL	Displacement of 1,8-ANS from mFABP by fluorescence based-assay	B	6.6	pKi	250	nM	Ki	Bioorg Med Chem Lett (2007) 17: 3511-3515 [PMID:17502136]
ChEMBL	Inhibition of human FABP3 by 8-anilino-1-naphthalenesulfonic acid based fluorescence displacement assay	B	4.83	pIC50	14700	nM	IC50	Bioorg Med Chem Lett (2013) 23: 1662-1666 [PMID:23395658]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]