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ChEMBL ligand: CHEMBL1200686 (Elidel, (-)-pimecrolimus, Pimecrolimus, SDZ ASM 981, SDZ ASM-981, SDZ-ASM 981, SDZ-ASM-981) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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FKBP prolyl isomerase 1A in Rat [GtoPdb: 2609] [UniProtKB: Q62658] | ||||||||
GtoPdb | Indirect measurement of primary target inhibition via rotamase inhibition | - | 8.22 | pIC50 | 6 | nM | IC50 | Arch Dermatol Res (1998) 290: 501-7 [PMID:9808344] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]