dodecyl-thiophosphate [Ligand Id: 6990] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL191365 (Thiophosphoric Acid Dodecyl Ester) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| LPA2 receptor/Lysophosphatidic acid receptor Edg-4 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3724] [GtoPdb: 273] [UniProtKB: Q9HBW0] | ||||||||
| ChEMBL | Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA2 receptor | F | 6 | pEC50 | 1000 | nM | EC50 | J Med Chem (2005) 48: 4919-4930 [PMID:16033271] |
| LPA2 receptor in Mouse [GtoPdb: 273] [UniProtKB: Q9JL06] | ||||||||
| GtoPdb | - | - | 6 | pEC50 | 1000 | nM | EC50 | J Med Chem (2005) 48: 4919-30 [PMID:16033271] |
| LPA3 receptor/Lysophosphatidic acid receptor Edg-7 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3250] [GtoPdb: 274] [UniProtKB: Q9UBY5] | ||||||||
| ChEMBL | Binding affinity for Lysophosphatidic acid receptor 3 expressed in RH7777 rat hepatoma cells | B | 7.85 | pKi | 14 | nM | Ki | J Med Chem (2005) 48: 4919-4930 [PMID:16033271] |
| ChEMBL | Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA3 receptor | F | 7.55 | pIC50 | 28 | nM | IC50 | J Med Chem (2005) 48: 4919-4930 [PMID:16033271] |
| LPA3 receptor in Mouse [GtoPdb: 274] [UniProtKB: Q9EQ31] | ||||||||
| GtoPdb | - | - | 7.89 | pKi | 13 | nM | Ki | J Med Chem (2005) 48: 4919-30 [PMID:16033271] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
