isocarboxazid [Ligand Id: 7204] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL1201168 (Enerzer, Isocarboxazid, Marplan, NSC-169893, RO 5-0831, RO-5-0831) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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| 8-oxoguanine DNA glycosylase/N-glycosylase/DNA lyase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3396944] [GtoPdb: 3060] [UniProtKB: O15527] | ||||||||
| ChEMBL | Inhibition of human OGG1 incubated for 30 mins using 8-oxo-Gua-containing substrate by TAMRA fluorescence-based assay | B | 4.3 | pIC50 | >50000 | nM | IC50 | US-20170038365-A1. Small molecule inhibitors of 8-oxoguanine dna glycosylase-1 (ogg1) (null) |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
