ulipristal acetate [Ligand Id: 7460] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL260538 (CDB-2914, Ella, Ellaone, Esmya, PGL-4001, RTI-3021-012, Ulipristal acet, Ulipristal acetate, Ulipristal acetate, VA-2914, VA2914) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Progesterone receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL208] [GtoPdb: 627] [UniProtKB: P06401] | ||||||||
| ChEMBL | Antagonist activity at human PRB expressed in CHO cells assessed as inhibition of Org 2058 induced-transactivation | F | 9.7 | pIC50 | 0.2 | nM | IC50 | Bioorg Med Chem (2008) 16: 2753-2763 [PMID:18243712] |
| GtoPdb | - | - | 9.7 | pIC50 | 0.2 | nM | IC50 | Bioorg Med Chem (2008) 16: 2753-63 [PMID:18243712] |
| GtoPdb | - | - | 7 | pEC50 | >100 | nM | EC50 | Bioorg Med Chem (2008) 16: 2753-63 [PMID:18243712] |
| ChEMBL | Agonist activity at human PRB expressed in CHO cells | F | 7 | pEC50 | >100 | nM | EC50 | Bioorg Med Chem (2008) 16: 2753-2763 [PMID:18243712] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
