ChEMBL ligand: CHEMBL1522313
bromodomain and PHD finger containing 3/Bromodomain and PHD finger-containing protein 3 in Human [ChEMBL: CHEMBL3108644] [GtoPdb: 2731] [UniProtKB: Q9ULD4] There should be some charts here, you may need to enable JavaScript!
bromodomain containing 1/Bromodomain-containing protein 1 in Human [ChEMBL: CHEMBL2176774] [GtoPdb: 2724] [UniProtKB: O95696] There should be some charts here, you may need to enable JavaScript!
bromodomain containing 4/Bromodomain-containing protein 4 in Human [ChEMBL: CHEMBL1163125] [GtoPdb: 1945] [UniProtKB: O60885] There should be some charts here, you may need to enable JavaScript!
bromodomain and PHD finger containing 1/Peregrin in Human [ChEMBL: CHEMBL3132741] [GtoPdb: 2730] [UniProtKB: P55201] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
bromodomain and PHD finger containing 3/Bromodomain and PHD finger-containing protein 3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3108644] [GtoPdb: 2731] [UniProtKB: Q9ULD4]
ChEMBL	Binding affinity to 6H-Flag-tagged Tev-BRPF3 (579-706 aa) (unknown origin) by TR-FRET competitive assay	B	4	pIC50	>100000	nM	IC50	ACS Med Chem Lett (2014) 5: 1190-1195 [PMID:25408830]
bromodomain containing 1/Bromodomain-containing protein 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2176774] [GtoPdb: 2724] [UniProtKB: O95696]
ChEMBL	Binding affinity to 6H-Flag-tagged Tev-BRPF2 (551-673 aa) (unknown origin) by TR-FRET competitive assay	B	5.1	pIC50	7943.28	nM	IC50	ACS Med Chem Lett (2014) 5: 1190-1195 [PMID:25408830]
bromodomain containing 4/Bromodomain-containing protein 4 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1163125] [GtoPdb: 1945] [UniProtKB: O60885]
ChEMBL	Binding affinity to 6His-tagged-BRD4 BD1 Y390A mutant (1 to 477 aa) (unknown origin) by TR-FRET competitive assay	B	4.3	pIC50	>50118.72	nM	IC50	ACS Med Chem Lett (2014) 5: 1190-1195 [PMID:25408830]
ChEMBL	Binding affinity to 6-His-tagged-BRD4 (1 to 477 aa) Y97A mutant (unknown origin) by TR-FRET competitive assay	B	5.5	pIC50	3162.28	nM	IC50	ACS Med Chem Lett (2014) 5: 1190-1195 [PMID:25408830]
GtoPdb	-	-	7.1	pIC50	79.4	nM	IC50	ACS Med Chem Lett (2014) 5: 1190-1195 [PMID:25408830]
bromodomain and PHD finger containing 1/Peregrin in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3132741] [GtoPdb: 2730] [UniProtKB: P55201]
GtoPdb	-	-	4.3	pIC50	>50118	nM	IC50	ACS Med Chem Lett (2014) 5: 1190-1195 [PMID:25408830]
ChEMBL	Binding affinity to NanoLuc-tagged BRPF1 isoform 1 bromodomain (625-735 aa) (unknown origin) expressed in HEK293 cells co-transfected with histone H3.3-HaloTag after 18 hrs by NanoBRET assay	B	6	pIC50	1000	nM	IC50	ACS Med Chem Lett (2014) 5: 1190-1195 [PMID:25408830]
ChEMBL	Binding affinity to NanoLuc-tagged BRPF1 isoform 1 bromodomain (625-735 aa) (unknown origin) expressed in HEK293 cells co-transfected with histone H3.3-HaloTag after 18 hrs by NanoBRET assay	B	6.01	pIC50	980	nM	IC50	ACS Med Chem Lett (2014) 5: 1190-1195 [PMID:25408830]
ChEMBL	Binding affinity to 6H-Flag-tagged Tev-BRPF1 (622-738 aa) (unknown origin) by TR-FRET competitive assay	B	7.1	pIC50	79.43	nM	IC50	ACS Med Chem Lett (2014) 5: 1190-1195 [PMID:25408830]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]