compound 35 [PMID: 22902653] [Ligand Id: 8119] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL2070619 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| testis associated actin remodelling kinase 1/Dual specificity testis-specific protein kinase 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5604] [GtoPdb: 2239] [UniProtKB: Q15569] | ||||||||
| GtoPdb | - | - | 4.52 | pIC50 | >30000 | nM | IC50 | Bioorg Med Chem Lett (2012) 22: 5995-8 [PMID:22902653] |
| ChEMBL | Inhibition of TESK1 | B | 4.52 | pIC50 | >30000 | nM | IC50 | Bioorg Med Chem Lett (2012) 22: 5995-5998 [PMID:22902653] |
| testis associated actin remodelling kinase 2/Dual specificity testis-specific protein kinase 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2069163] [GtoPdb: 2240] [UniProtKB: Q96S53] | ||||||||
| GtoPdb | - | - | 4.52 | pIC50 | >30000 | nM | IC50 | Bioorg Med Chem Lett (2012) 22: 5995-8 [PMID:22902653] |
| ChEMBL | Inhibition of TESK2 | B | 4.52 | pIC50 | >30000 | nM | IC50 | Bioorg Med Chem Lett (2012) 22: 5995-5998 [PMID:22902653] |
| LIM domain kinase 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3836] [GtoPdb: 2054] [UniProtKB: P53667] | ||||||||
| GtoPdb | - | - | 7.52 | pIC50 | 30 | nM | IC50 | Bioorg Med Chem Lett (2012) 22: 5995-8 [PMID:22902653] |
| ChEMBL | Inhibition of LIMK1 | B | 7.52 | pIC50 | 30 | nM | IC50 | Bioorg Med Chem Lett (2012) 22: 5995-5998 [PMID:22902653] |
| LIM domain kinase 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5932] [GtoPdb: 2055] [UniProtKB: P53671] | ||||||||
| ChEMBL | Inhibition of LIMK2 | B | 8.1 | pIC50 | 8 | nM | IC50 | Bioorg Med Chem Lett (2012) 22: 5995-5998 [PMID:22902653] |
| GtoPdb | - | - | 8.1 | pIC50 | 8 | nM | IC50 | Bioorg Med Chem Lett (2012) 22: 5995-8 [PMID:22902653] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
