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ChEMBL ligand: CHEMBL426445 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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ribosomal protein S6 kinase B2/Ribosomal protein S6 kinase 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3111] [GtoPdb: 1526] [UniProtKB: Q9UBS0] | ||||||||
ChEMBL | In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5''-[gamma-33P]-triphosphate | B | 7.4 | pIC50 | 40 | nM | IC50 | Bioorg Med Chem Lett (2005) 15: 3241-3246 [PMID:15925511] |
SRSF protein kinase 1/Serine/threonine-protein kinase SRPK1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4375] [GtoPdb: 2208] [UniProtKB: Q96SB4] | ||||||||
ChEMBL | Inhibition of SRPK1 kinase (unknown origin) | B | 7.4 | pIC50 | 40 | nM | IC50 | Eur J Med Chem (2014) 85: 688-715 [PMID:25128670] |
GtoPdb | - | - | 7.4 | pIC50 | 40 | nM | IC50 | Bioorg Med Chem Lett (2005) 15: 3241-6 [PMID:15925511] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]