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ChEMBL ligand: CHEMBL2203524 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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serine/threonine kinase 33/Serine/threonine-protein kinase 33 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL6005] [GtoPdb: 2221] [UniProtKB: Q9BYT3] | ||||||||
GtoPdb | - | - | 8.15 | pIC50 | 7 | nM | IC50 | Cancer Res (2011) 71: 5818-26 [PMID:21742770] |
ChEMBL | Inhibition of N-terminal 6His-tagged full length human recombinant STK33 using myelin basic protein as substrate incubated for 15 mins before initiation of kinase reaction measured after 1 hr by ADP-glo assay | B | 8.15 | pIC50 | 7 | nM | IC50 | ACS Med Chem Lett (2012) 3: 1034-1038 [PMID:23256033] |
protein kinase A in Human [GtoPdb: 1694] | ||||||||
GtoPdb | - | - | 6.71 | pIC50 | 196 | nM | IC50 | ACS Med Chem Lett (2012) 3: 1034-1038 [PMID:23256033] |
aurora kinase B in Human [GtoPdb: 1937] [UniProtKB: Q96GD4] | ||||||||
GtoPdb | - | - | 8.55 | pIC50 | 2.8 | nM | IC50 | ACS Med Chem Lett (2012) 3: 1034-1038 [PMID:23256033] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]