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ChEMBL ligand: CHEMBL447457 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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MMP11/Matrix metalloproteinase 11 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2867] [GtoPdb: 1635] [UniProtKB: P24347] | ||||||||
GtoPdb | - | - | 6.64 | pKi | 230 | nM | Ki | Bioorg Med Chem (2008) 16: 8781-94 [PMID:18790648] |
ChEMBL | Inhibition of MMP11 | B | 9.64 | pKi | 0.23 | nM | Ki | Bioorg Med Chem (2008) 16: 8781-8794 [PMID:18790648] |
MMP13/Matrix metalloproteinase 13 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL280] [GtoPdb: 1637] [UniProtKB: P45452] | ||||||||
ChEMBL | Inhibition of MMP13 | B | 7.8 | pKi | 15.7 | nM | Ki | Bioorg Med Chem (2008) 16: 8781-8794 [PMID:18790648] |
MMP14/Matrix metalloproteinase 14 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3869] [GtoPdb: 1638] [UniProtKB: P50281] | ||||||||
ChEMBL | Inhibition of MMP14 | B | 6.8 | pKi | 160 | nM | Ki | Bioorg Med Chem (2008) 16: 8781-8794 [PMID:18790648] |
MMP2/Matrix metalloproteinase-2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL333] [GtoPdb: 1629] [UniProtKB: P08253] | ||||||||
ChEMBL | Inhibition of MMP2 | B | 7.52 | pKi | 30 | nM | Ki | Bioorg Med Chem (2008) 16: 8781-8794 [PMID:18790648] |
MMP8/Matrix metalloproteinase 8 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4588] [GtoPdb: 1632] [UniProtKB: P22894] | ||||||||
ChEMBL | Inhibition of MMP8 | B | 7.41 | pKi | 38.9 | nM | Ki | Bioorg Med Chem (2008) 16: 8781-8794 [PMID:18790648] |
MMP9/Matrix metalloproteinase 9 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL321] [GtoPdb: 1633] [UniProtKB: P14780] | ||||||||
ChEMBL | Inhibition of MMP9 | B | 7.45 | pKi | 35.6 | nM | Ki | Bioorg Med Chem (2008) 16: 8781-8794 [PMID:18790648] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]