compound 28xvii [PMID: 8809154] [Ligand Id: 8764] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL331755 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| sPLA2-1B/Phospholipase A2 group 1B in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4426] [GtoPdb: 1416] [UniProtKB: P04054] | ||||||||
| ChEMBL | Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay. | B | 8.22 | pIC50 | 6 | nM | IC50 | J Med Chem (1996) 39: 3636-3658 [PMID:8809154] |
| ChEMBL | Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC). | B | 8.89 | pIC50 | 1.3 | nM | IC50 | J Med Chem (1996) 39: 3636-3658 [PMID:8809154] |
| GtoPdb | Measured using a chromogenic assay. | - | 8.89 | pIC50 | 1.3 | nM | IC50 | J Med Chem (1996) 39: 3636-58 [PMID:8809154] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
