compound 5 [PMID: 21838328] [Ligand Id: 8790] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL1831083 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| CYP26A1/Cytochrome P450 26A1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5141] [GtoPdb: 1366] [UniProtKB: O43174] | ||||||||
| ChEMBL | Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation counting | B | 9.46 | pIC50 | 0.35 | nM | IC50 | J Med Chem (2011) 54: 6803-6811 [PMID:21838328] |
| GtoPdb | Measuring retinoic acid metabolism in a cell-free microsomal assay. | - | 9.46 | pIC50 | 0.35 | nM | IC50 | J Med Chem (2011) 54: 6803-11 [PMID:21838328] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
