compound 5k [PMID: 23528296] [Ligand Id: 8801] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL2377621 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Fatty acid transport protein 1/Long-chain fatty acid transport protein 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2052038] [GtoPdb: 1108] [UniProtKB: Q6PCB7] | ||||||||
| ChEMBL | Inhibition of human FLAG-tagged FATP1-mediated [1-14C] oleic acid conversion to [1-14C] oleoyl-CoA after 20 mins by scintillation counting analysis | B | 7.34 | pIC50 | 46 | nM | IC50 | Bioorg Med Chem Lett (2013) 23: 2560-2565 [PMID:23528296] |
| GtoPdb | - | - | 7.34 | pIC50 | 46 | nM | IC50 | Bioorg Med Chem Lett (2013) 23: 2560-5 [PMID:23528296] |
| Fatty acid transport protein 1/Long-chain fatty acid transport protein 1 in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2052039] [GtoPdb: 1108] [UniProtKB: Q60714] | ||||||||
| ChEMBL | Inhibition of mouse FLAG-tagged FATP1-mediated [1-14C] oleic acid conversion to [1-14C] oleoyl-CoA after 20 mins by scintillation counting analysis | B | 6.22 | pIC50 | 600 | nM | IC50 | Bioorg Med Chem Lett (2013) 23: 2560-2565 [PMID:23528296] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
