naphthylvinylmethylpyridine [Ligand Id: 8807] activity data from GtoPdb and ChEMBL
Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
| ChEMBL ligand: CHEMBL106212 |
|---|
There should be some charts here, you may need to enable JavaScript!
|
| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| choline O-acetyltransferase/Choline acetylase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4039] [GtoPdb: 2480] [UniProtKB: P28329] | ||||||||
| ChEMBL | Inhibition of Choline Acetyltransferase | B | 6.4 | pIC50 | 400 | nM | IC50 | J Med Chem (1994) 37: 3128-3131 [PMID:7932536] |
| choline O-acetyltransferase in Mouse [GtoPdb: 2480] [UniProtKB: Q03059] | ||||||||
| GtoPdb | - | - | 6.47 | pIC50 | 340 | nM | IC50 | J Med Chem (1988) 31: 807-14 [PMID:3351860] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
