compound D24 [PMID: 24374347] [Ligand Id: 8834] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL1509437 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| sphingomyelin synthase 2/Phosphatidylcholine:ceramide cholinephosphotransferase 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3112379] [GtoPdb: 2521] [UniProtKB: Q8NHU3] | ||||||||
| ChEMBL | Inhibition of SMS2 (unknown origin) expressed in H5 insect cells using C6-NBD-Cer as substrate after 1 hr | B | 4.91 | pIC50 | 12400 | nM | IC50 | Eur J Med Chem (2014) 73: 1-7 [PMID:24374347] |
| GtoPdb | - | - | 4.91 | pIC50 | 12400 | nM | IC50 | Eur J Med Chem (2014) 73: 1-7 [PMID:24374347] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
