compound 7a [PMID: 24884590] [Ligand Id: 8840] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL3299119 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| GPR52/Probable G-protein coupled receptor 52 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3297639] [GtoPdb: 108] [UniProtKB: Q9Y2T5] | ||||||||
| GtoPdb | - | - | 7.55 | pEC50 | 28.2 | nM | EC50 | J Med Chem (2014) 57: 5226-37 [PMID:24884590] |
| ChEMBL | Agonist activity at human GPR52 expressed in CHO cells assessed as cAMP production after 30 mins by Alphascreen assay | F | 7.55 | pEC50 | 28.18 | nM | EC50 | J Med Chem (2014) 57: 5226-5237 [PMID:24884590] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
