ChEMBL ligand: CHEMBL25230 (BW-373U86, SNC-86)
δ receptor/Delta opioid receptor in Human [ChEMBL: CHEMBL236] [GtoPdb: 317] [UniProtKB: P41143] δ receptor/Delta opioid receptor in Mouse [ChEMBL: CHEMBL3222] [GtoPdb: 317] [UniProtKB: P32300] δ receptor/Delta opioid receptor in Rat [ChEMBL: CHEMBL269] [GtoPdb: 317] [UniProtKB: P33533] There should be some charts here, you may need to enable JavaScript!
κ receptor/Kappa opioid receptor in Human [ChEMBL: CHEMBL237] [GtoPdb: 318] [UniProtKB: P41145] κ receptor in Rat [GtoPdb: 318] [UniProtKB: P34975] There should be some charts here, you may need to enable JavaScript!
μ receptor/Mu opioid receptor in Human [ChEMBL: CHEMBL233] [GtoPdb: 319] [UniProtKB: P35372] μ receptor/Mu opioid receptor in Rat [ChEMBL: CHEMBL270] [GtoPdb: 319] [UniProtKB: P33535] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
δ receptor/Delta opioid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL236] [GtoPdb: 317] [UniProtKB: P41143]
GtoPdb	-	-	9.49	pKi	0.32	nM	Ki	J Med Chem (2008) 51: 5893-6 [PMID:18788723]
ChEMBL	Displacement of [3H]diprenorphine from human delta opioid receptor in CHO cells	B	9.49	pKi	0.32	nM	Ki	J Med Chem (2008) 51: 5893-5896 [PMID:18788723]
ChEMBL	Binding affinity against human opioid receptor delta 1 using [125I]-[D-Ala2]-deltorphin II as radioligand	B	9.64	pIC50	0.23	nM	IC50	J Med Chem (2000) 43: 3878-3894 [PMID:11052793]
ChEMBL	Agonist activity at human delta opioid receptor in CHO cells assessed as stimulation of [35S]GTPgammaS binding	F	9.4	pEC50	0.4	nM	EC50	J Med Chem (2008) 51: 5893-5896 [PMID:18788723]
ChEMBL	Agonist potency was measured using GTP gamma-[35S] binding assay	B	9.92	pEC50	0.12	nM	EC50	J Med Chem (2000) 43: 3878-3894 [PMID:11052793]
δ receptor/Delta opioid receptor in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3222] [GtoPdb: 317] [UniProtKB: P32300]
ChEMBL	Binding affinity towards opioid Delta receptor using [3H]DADLE as radioligand	B	9.04	pKi	0.91	nM	Ki	Bioorg Med Chem Lett (1999) 9: 3053-3056 [PMID:10571174]
ChEMBL	Binding affinity towards opioid Delta receptor using [3H]DADLE as radioligand	B	9.04	pKi	0.91	nM	Ki	Bioorg Med Chem Lett (1999) 9: 3347-3350 [PMID:10612597]
ChEMBL	Agonist activity at delta opioid receptor in mouse vas deferens	F	9.2	pIC50	0.63	nM	IC50	Bioorg Med Chem Lett (2006) 16: 905-910 [PMID:16290934]
ChEMBL	Tested for inhibition of binding of [3H]DADLE to mouse brain membranes depleted of mu binding sites by pretreatment with irreversible ligand BIT for delta opioid receptor	B	9.51	pIC50	0.31	nM	IC50	J Med Chem (1994) 37: 2125-2128 [PMID:8035418]
δ receptor/Delta opioid receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL269] [GtoPdb: 317] [UniProtKB: P33533]
GtoPdb	-	-	8.74	pKi	1.8	nM	Ki	J Pharmacol Exp Ther (1993) 267: 852-7 [PMID:8246159]
ChEMBL	Binding affinity of compound evaluated for Opioid receptor delta 1 isolated from rat brain	B	8.74	pKi	1.8	nM	Ki	J Med Chem (2003) 46: 623-633 [PMID:12570383]
ChEMBL	Affinity of [H]DADLE to the delta opioid receptor from rat brain	B	9.04	pKi	0.91	nM	Ki	J Med Chem (2001) 44: 972-987 [PMID:11300879]
ChEMBL	Inhibition of radioligand [3H]DADLE binding to rat brain Opioid receptor delta 1	B	7.23	pIC50	58.3	nM	IC50	J Med Chem (1997) 40: 695-704 [PMID:9057856]
ChEMBL	Inhibition of radioligand [3H]DADLE binding to rat brain Opioid receptor delta 1	B	8.83	pIC50	1.49	nM	IC50	J Med Chem (1997) 40: 695-704 [PMID:9057856]
ChEMBL	Binding affinity was measured against Opioid receptor delta 1 using [3H]p-Cl-DPDPE as radioligand.	B	9.51	pIC50	0.31	nM	IC50	J Med Chem (1998) 41: 4767-4776 [PMID:9822547]
κ receptor/Kappa opioid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL237] [GtoPdb: 318] [UniProtKB: P41145]
ChEMBL	Displacement of [3H]diprenorphine from human kappa opioid receptor in CHO cells	B	5.47	pKi	3400	nM	Ki	J Med Chem (2008) 51: 5893-5896 [PMID:18788723]
ChEMBL	Displacement of [3H]diprenorphine from human kappa opioid receptor in CHO cells at 10 uM	B	6.89	pKi	130	nM	Ki	J Med Chem (2008) 51: 5893-5896 [PMID:18788723]
GtoPdb	-	-	6.89	pKi	130	nM	Ki	J Med Chem (2008) 51: 5893-6 [PMID:18788723]
ChEMBL	Binding affinity against cloned human Opioid receptor kappa 1 using [125I]-D-Pro10-dynorphin A[1-11] as radioligand	B	7.7	pIC50	20	nM	IC50	J Med Chem (2000) 43: 3878-3894 [PMID:11052793]
κ receptor in Rat [GtoPdb: 318] [UniProtKB: P34975]
GtoPdb	-	-	7.47	pKi	34	nM	Ki	J Pharmacol Exp Ther (1993) 267: 852-7 [PMID:8246159]
μ receptor/Mu opioid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL233] [GtoPdb: 319] [UniProtKB: P35372]
ChEMBL	Displacement of [3H]diprenorphine from human mu opioid receptor in CHO cells	B	6.59	pKi	260	nM	Ki	J Med Chem (2008) 51: 5893-5896 [PMID:18788723]
GtoPdb	-	-	6.59	pKi	260	nM	Ki	J Med Chem (2008) 51: 5893-6 [PMID:18788723]
ChEMBL	Binding affinity against cloned human Opioid receptor mu 1 using [125I]FK33824 as radioligand	B	8.68	pIC50	2.1	nM	IC50	J Med Chem (2000) 43: 3878-3894 [PMID:11052793]
μ receptor/Mu opioid receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL270] [GtoPdb: 319] [UniProtKB: P33535]
ChEMBL	Affinity of [3H]DAMGO to the mu opioid receptor from rat brain	B	7.44	pKi	36	nM	Ki	J Med Chem (2001) 44: 972-987 [PMID:11300879]
ChEMBL	Binding affinity towards opioid Mu receptor using [3H]DAMGO as radioligand	B	7.44	pKi	36	nM	Ki	Bioorg Med Chem Lett (1999) 9: 3053-3056 [PMID:10571174]
ChEMBL	Binding affinity towards opioid Mu receptor using [3H]DAMGO as radioligand	B	7.44	pKi	36	nM	Ki	Bioorg Med Chem Lett (1999) 9: 3347-3350 [PMID:10612597]
GtoPdb	-	-	7.82	pKi	15	nM	Ki	J Pharmacol Exp Ther (1993) 267: 852-7 [PMID:8246159]
ChEMBL	Inhibition of [3H]DAMGO binding to mu opioid receptor of rat brain membranes	B	7.82	pKi	15	nM	Ki	J Med Chem (2003) 46: 623-633 [PMID:12570383]
ChEMBL	Inhibition of radioligand [3H]DAMGO binding to rat brain Opioid receptor mu 1 using 100 nM DAMGO	B	5.63	pIC50	2322	nM	IC50	J Med Chem (1997) 40: 695-704 [PMID:9057856]
ChEMBL	Inhibition of radioligand [3H]DAMGO binding to rat brain Opioid receptor mu 1 using 100 nM DAMGO	B	8.01	pIC50	9.71	nM	IC50	J Med Chem (1997) 40: 695-704 [PMID:9057856]
ChEMBL	Evaluated for inhibition of [3H]DAMGO binding from mu receptor in rat brain membranes	B	8.01	pIC50	9.71	nM	IC50	J Med Chem (1994) 37: 2125-2128 [PMID:8035418]
ChEMBL	Binding affinity was measured against Opioid receptor mu 1 using [3H]-DAMGO as radioligand.	B	8.01	pIC50	9.7	nM	IC50	J Med Chem (1998) 41: 4767-4776 [PMID:9822547]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]