BRD3444 [Ligand Id: 9648] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL3560390 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Plasmodium falciparum phenylalanyl-tRNA synthetase alpha subunit in Plasmodium berghei [GtoPdb: 2954] | ||||||||
| GtoPdb | Parasite liver stage assay | - | 6.85 | pEC50 | 140 | nM | EC50 | Nature (2016) 538: 344-349 [PMID:27602946] |
| Plasmodium falciparum phenylalanyl-tRNA synthetase alpha subunit in Plasmodium falciparum [GtoPdb: 2954] | ||||||||
| GtoPdb | - | - | 7.34 | pIC50 | 46 | nM | IC50 | Nature (2016) 538: 344-349 [PMID:27602946] |
| Plasmodium falciparum phenylalanyl-tRNA synthetase alpha subunit in Plasmodium falciparum 3D7 [GtoPdb: 2954] [UniProtKB: Q8I246] | ||||||||
| GtoPdb | Parasite late stage (IV–V) gametocyte assay | - | 6.18 | pEC50 | 663 | nM | EC50 | Nature (2016) 538: 344-349 [PMID:27602946] |
| Plasmodium falciparum phenylalanyl-tRNA synthetase alpha subunit in Plasmodium falciparum Dd2 [GtoPdb: 2954] | ||||||||
| GtoPdb | Parasite growth inhibition assay | - | 8.05 | pEC50 | 9 | nM | EC50 | Nature (2016) 538: 344-349 [PMID:27602946] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
